MECP2 germline mosaicism plays an important part in the inheritance of Rett syndrome: a study of MECP2 germline mosaicism in males

MECP2 germline mosaicism plays an important part in the inheritance of Rett syndrome: a study of MECP2 germline mosaicism in males

Abstract Background Germline mosaicisms could be inherited to offspring, which considered as “de novo” in most cases. Paternal germline MECP2 mosaicism has been reported in fathers of girls with Rett syndrome (RTT) previously. For further study, we focused on MECP2 germline mosaicism in males, not o...

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Bibliographic Details
Main Authors:	Yongxin Wen, Jiaping Wang, Qingping Zhang, Xiaoxu Yang, Liping Wei, Xinhua Bao
Format:	Article
Language:	English
Published:	BMC 2023-04-01
Series:	BMC Medicine
Subjects:	MECP2 Mosaicism Germline De novo Rett syndrome
Online Access:	https://doi.org/10.1186/s12916-023-02846-2

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