A randomized sham-controlled trial of high-dosage accelerated intermittent theta burst rTMS in major depression: study protocol

A randomized sham-controlled trial of high-dosage accelerated intermittent theta burst rTMS in major depression: study protocol

Abstract Background Intermittent theta burst stimulation (iTBS), a novel form of repetitive transcranial magnetic stimulation (rTMS), can be administered in 1/10th of the time of standard rTMS (~ 3 min vs. 37.5 min) yet achieves similar outcomes in depression. The brief nature of the iTBS protocol a...

Full description

Bibliographic Details
Main Authors:	Michelle S. Goodman, Fidel Vila-Rodriguez, Melanie Barwick, Matthew J. Burke, Jonathan Downar, Jonathan Hunter, Tyler S. Kaster, Yuliya Knyahnytska, Paul Kurdyak, Robert Maunder, Kevin Thorpe, Alisson P. Trevizol, Daphne Voineskos, Wei Zhang, Daniel M. Blumberger
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Series:	BMC Psychiatry
Subjects:	Repetitive transcranial magnetic stimulation (rTMS) Accelerated intermittent theta burst stimulation (aiTBS) Treatment-resistant depression (TRD)
Online Access:	https://doi.org/10.1186/s12888-023-05470-9

Similar Items

Symptom improvement is associated with serum cytokine level change during RTMS tretament in patients with treatment resistant depression
by: J. Lazary, et al.
Published: (2021-04-01)

A chart-based study of theta burst stimulation for depression at a tertiary care center
by: Sachin Pradeep Baliga, et al.
Published: (2020-11-01)

Prolonged Continuous Theta Burst Stimulation of the Motor Cortex Modulates Cortical Excitability But not Pain Perception
by: Monika Klírová, et al.
Published: (2020-05-01)

Unchanged Cognitive Performance and Concurrent Prefrontal Blood Oxygenation After Accelerated Intermittent Theta-Burst Stimulation in Depression: A Sham-Controlled Study
by: Wiebke Struckmann, et al.
Published: (2021-06-01)

Neurophysiological impact of theta burst stimulation followed by cognitive exercise in treatment of youth depression
by: Prabhjot Dhami, et al.
Published: (2022-12-01)

Subthreshold stimulation intensity is associated with greater clinical efficacy of intermittent theta-burst stimulation priming for Major Depressive Disorder
by: Jonathan C. Lee, et al.
Published: (2021-07-01)

Continuous theta burst stimulation at 30 hz does not modulate cortical excitability in a sham-controlled study
by: Joana Frieske, et al.
Published: (2024-12-01)

Activate & fire: a feasibility study in combining acoustic stimulation and continuous theta burst stimulation in chronic tinnitus
by: Stefan Schoisswohl, et al.
Published: (2023-01-01)

Treatment of depression in the elderly with repetitive transcranial magnetic stimulation using theta-burst stimulation: Study protocol for a randomized, double-blind, controlled trial
by: Leandro Valiengo, et al.
Published: (2022-08-01)

Efficacy and safety of intermittent theta burst stimulation (iTBS) in treatment resistant depression
by: E. Kavakbasi, et al.
Published: (2022-06-01)

Non-Invasive Brain Stimulation for the Modulation of Aggressive Behavior—A Systematic Review of Randomized Sham-Controlled Studies
by: Antony Casula, et al.
Published: (2023-05-01)

Treatment of Spider Phobia Using Repeated Exposures and Adjunctive Repetitive Transcranial Magnetic Stimulation: A Proof-of-Concept Study
by: Michael K. Leuchter, et al.
Published: (2022-03-01)

A case series of a novel 1 Hz right-sided dorsolateral prefrontal cortex rTMS protocol in major depression
by: Jean-Philippe Miron, et al.
Published: (2020-03-01)

Intermittent theta burst stimulation enhances upper limb motor function in patients with chronic stroke: a pilot randomized controlled trial
by: Yu-Jen Chen, et al.
Published: (2019-04-01)

Effects of iTBS-rTMS on the Behavioral Phenotype of a Rat Model of Maternal Immune Activation
by: Nadine Rittweger, et al.
Published: (2021-04-01)

rTMS for Tinnitus
by: Robert eFolmer
Published: (2012-01-01)

The effect of pulse shape in theta-burst stimulation: Monophasic vs biphasic TMS
by: Karen Wendt, et al.
Published: (2023-07-01)

A randomized sham controlled comparison of once vs twice-daily intermittent theta burst stimulation in depression: A Canadian rTMS treatment and biomarker network in depression (CARTBIND) study
by: Daniel M. Blumberger, et al.
Published: (2021-11-01)

Accelerated iTBS treatment applied to the left DLPFC in depressed patients results in a rapid volume increase in the left hippocampal dentate gyrus, not driven by brain perfusion
by: Chris Baeken, et al.
Published: (2020-09-01)

Bilateral sequential theta burst stimulation in depressed veterans with service related posttraumatic stress disorder: a feasibility study
by: Thelepa Vaithianathan, et al.
Published: (2022-02-01)

Polysomnographically mediated cognitive improvements in individuals with insomnia symptoms following continuous theta-burst stimulation of the default mode network
by: Alisa Huskey, et al.
Published: (2024-10-01)

Continuous and intermittent theta burst stimulation of primary visual cortex do not modulate resting state functional connectivity: A sham‐controlled multi‐echo fMRI study
by: Remy Cohan, et al.
Published: (2023-05-01)

Effect of 30 Hz Theta Burst Transcranial Magnetic Stimulation on the Primary Motor Cortex in Children and Adolescents
by: Ernest ePedapati, et al.
Published: (2015-02-01)

Antidepressant response time across intermittent theta burst stimulation regimens and efficacy indicators in adolescents depression: a secondary analysis from a randomized controlled trial
by: Min Zhang, et al.
Published: (2024-12-01)

Effects on impulsivity and delay discounting of intermittent theta burst stimulation add-on to dialectical behavioral therapy in borderline personality disorder: a randomized, sham-controlled pilot trial
by: Milenko Kujovic, et al.
Published: (2025-01-01)

Transcranial magnetic stimulation and intravenous ketamine combination therapy for treatment-resistant bipolar depression: A case report
by: Laurent Elkrief, et al.
Published: (2022-09-01)

Efficacy of repetitive transcranial magnetic stimulation (rTMS) adjunctive therapy for major depressive disorder (MDD) after two antidepressant treatment failures: meta-analysis of randomized sham-controlled trials
by: Róbert György Vida, et al.
Published: (2023-07-01)

A patient-oriented analysis of pain side effect: A step to improve the patient's experience during rTMS?
by: Afifa Humaira, et al.
Published: (2021-09-01)

Effects of different transcranial magnetic stimulations on neuropathic pain after spinal cord injury
by: Chuanmei Yang, et al.
Published: (2023-07-01)

Revisiting Hemispheric Asymmetry in Mood Regulation: Implications for rTMS for Major Depressive Disorder
by: Benjamin C. Gibson, et al.
Published: (2022-01-01)

A randomized, double blind, sham-controlled trial of repetitive transcranial magnetic stimulation (rTMS) in the treatment of negative symptoms in schizophrenia
by: Nand Kumar, et al.
Published: (2020-05-01)

A naturalistic study comparing the efficacy of unilateral and bilateral sequential theta burst stimulation in treating major depression – the U-B-D study protocol
by: Molly Watson, et al.
Published: (2023-10-01)

Safety of low-intensity repetitive transcranial magneTic brAin stimUlation foR people living with mUltiple Sclerosis (TAURUS): study protocol for a randomised controlled trial
by: Kalina Makowiecki, et al.
Published: (2022-08-01)

Case report: Tremor in the placebo condition of a blinded clinical trial of intermittent theta-burst stimulation for cocaine use disorder
by: Vaughn R. Steele, et al.
Published: (2024-07-01)

Non-invasive central and peripheral stimulation: new hope for essential tremor?
by: Moussa A Chalah, et al.
Published: (2015-11-01)

Intermittent Theta-Burst Stimulation Over the DorsoLateral PreFrontal Cortex (DLPFC) in Healthy Subjects Produces No Cumulative Effect on Cortical Excitability
by: Noomane Bouaziz, et al.
Published: (2021-02-01)

Predictors for rTMS response in chronic tinnitus
by: Astrid eLehner, et al.
Published: (2012-02-01)

A direct comparison of neuronavigated and non-neuronavigated intermittent theta burst stimulation in the treatment of depression
by: Tobias Hebel, et al.
Published: (2021-03-01)

Depressive symptom trajectories with prolonged rTMS treatment
by: Xiao Chen, et al.
Published: (2024-05-01)

Transcranial Magnetic Stimulation as an Interventional Tool for Addiction
by: Vaughn R. Steele
Published: (2020-10-01)