Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes
The review includes the results of analytical research on the problem of application of pancreatic islet encapsulation technologies for compensation of type 1 diabetes. We present a review of modern encapsulation technologies, approaches to encapsulation strategies, insulin replacement technologies:...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2022-01-01
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| Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/1364 |
| _version_ | 1797871957864087552 |
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| author | P. S. Ermakova E. I. Cherkasova N. A. Lenshina A. N. Konev M. A. Batenkin S. A. Chesnokov D. M. Kuchin E. V. Zagainova V. E. Zagainov A. V. Kashina |
| author_facet | P. S. Ermakova E. I. Cherkasova N. A. Lenshina A. N. Konev M. A. Batenkin S. A. Chesnokov D. M. Kuchin E. V. Zagainova V. E. Zagainov A. V. Kashina |
| author_sort | P. S. Ermakova |
| collection | DOAJ |
| description | The review includes the results of analytical research on the problem of application of pancreatic islet encapsulation technologies for compensation of type 1 diabetes. We present a review of modern encapsulation technologies, approaches to encapsulation strategies, insulin replacement technologies: auto-, allo- and xenotransplantation; prospects for cell therapy for insulin-dependent conditions; modern approaches to β-cell encapsulation, possibilities of optimization of encapsulation biomaterials to increase survival of transplanted cells and reduce adverse consequences for the recipient. The main problems that need to be solved for effective transplantation of encapsulated islets of Langerhans are identified and the main strategies for translating the islet encapsulation technology into medical reality are outlined. |
| first_indexed | 2024-04-10T00:51:12Z |
| format | Article |
| id | doaj.art-c79fd45c70684f68a41f8ced4c0ccab4 |
| institution | Directory Open Access Journal |
| issn | 1995-1191 |
| language | Russian |
| last_indexed | 2024-04-10T00:51:12Z |
| publishDate | 2022-01-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Vestnik Transplantologii i Iskusstvennyh Organov |
| spelling | doaj.art-c79fd45c70684f68a41f8ced4c0ccab42023-03-13T10:37:28ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912022-01-012349510910.15825/1995-1191-2021-4-95-1091050Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetesP. S. Ermakova0E. I. Cherkasova1N. A. Lenshina2A. N. Konev3M. A. Batenkin4S. A. Chesnokov5D. M. Kuchin6E. V. Zagainova7V. E. Zagainov8A. V. Kashina9Privolzhsky Research Medical UniversityPrivolzhsky Research Medical University; Lobachevsky State University of Nizhny NovgorodRazuvaev Institute of Organometallic ChemistryRazuvaev Institute of Organometallic ChemistryRazuvaev Institute of Organometallic ChemistryRazuvaev Institute of Organometallic ChemistryPrivolzhsky District Medical CenterPrivolzhsky Research Medical University; Lobachevsky State University of Nizhny NovgorodPrivolzhsky Research Medical University; Privolzhsky District Medical CenterPrivolzhsky Research Medical UniversityThe review includes the results of analytical research on the problem of application of pancreatic islet encapsulation technologies for compensation of type 1 diabetes. We present a review of modern encapsulation technologies, approaches to encapsulation strategies, insulin replacement technologies: auto-, allo- and xenotransplantation; prospects for cell therapy for insulin-dependent conditions; modern approaches to β-cell encapsulation, possibilities of optimization of encapsulation biomaterials to increase survival of transplanted cells and reduce adverse consequences for the recipient. The main problems that need to be solved for effective transplantation of encapsulated islets of Langerhans are identified and the main strategies for translating the islet encapsulation technology into medical reality are outlined.https://journal.transpl.ru/vtio/article/view/1364pancreasislets of langerhansencapsulationtransplantationimmunosuppressiontype 1 diabetes |
| spellingShingle | P. S. Ermakova E. I. Cherkasova N. A. Lenshina A. N. Konev M. A. Batenkin S. A. Chesnokov D. M. Kuchin E. V. Zagainova V. E. Zagainov A. V. Kashina Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes Vestnik Transplantologii i Iskusstvennyh Organov pancreas islets of langerhans encapsulation transplantation immunosuppression type 1 diabetes |
| title | Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes |
| title_full | Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes |
| title_fullStr | Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes |
| title_full_unstemmed | Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes |
| title_short | Modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes |
| title_sort | modern pancreatic islet encapsulation technologies for the treatment of type 1 diabetes |
| topic | pancreas islets of langerhans encapsulation transplantation immunosuppression type 1 diabetes |
| url | https://journal.transpl.ru/vtio/article/view/1364 |
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