A CD4+ T cell reference map delineates subtype-specific adaptation during acute and chronic viral infections

A CD4+ T cell reference map delineates subtype-specific adaptation during acute and chronic viral infections

CD4+ T cells are critical orchestrators of immune responses against a large variety of pathogens, including viruses. While multiple CD4+ T cell subtypes and their key transcriptional regulators have been identified, there is a lack of consistent definition for CD4+ T cell transcriptional states. In...

Full description

Bibliographic Details
Main Authors: Massimo Andreatta, Ariel Tjitropranoto, Zachary Sherman, Michael C Kelly, Thomas Ciucci, Santiago J Carmona
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-07-01
Series:eLife
Subjects:
CD4 T cells
viral infection
gene expression
single-cell transcriptomics
exhaustion
single-cell data science
Online Access:https://elifesciences.org/articles/76339

Similar Items

Similar Items