Innate Lymphoid Cells in the Central Nervous System
Immune cells are present within the central nervous system and play important roles in neurological inflammation and disease. As relatively new described immune cell population, Innate Lymphoid Cells are now increasingly recognized within the central nervous system and associated diseases. Innate Ly...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-02-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.837250/full |
| _version_ | 1830340598514581504 |
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| author | Shuaiwei Wang Serge A. van de Pavert |
| author_facet | Shuaiwei Wang Serge A. van de Pavert |
| author_sort | Shuaiwei Wang |
| collection | DOAJ |
| description | Immune cells are present within the central nervous system and play important roles in neurological inflammation and disease. As relatively new described immune cell population, Innate Lymphoid Cells are now increasingly recognized within the central nervous system and associated diseases. Innate Lymphoid Cells are generally regarded as tissue resident and early responders, while conversely within the central nervous system at steady-state their presence is limited. This review describes the current understandings on Innate Lymphoid Cells in the central nervous system at steady-state and its borders plus their involvement in major neurological diseases like ischemic stroke, Alzheimer’s disease and Multiple Sclerosis. |
| first_indexed | 2024-12-19T21:17:45Z |
| format | Article |
| id | doaj.art-c7a1611100c546f5b77c48af7b31746b |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-19T21:17:45Z |
| publishDate | 2022-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-c7a1611100c546f5b77c48af7b31746b2022-12-21T20:05:18ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-02-011310.3389/fimmu.2022.837250837250Innate Lymphoid Cells in the Central Nervous SystemShuaiwei WangSerge A. van de PavertImmune cells are present within the central nervous system and play important roles in neurological inflammation and disease. As relatively new described immune cell population, Innate Lymphoid Cells are now increasingly recognized within the central nervous system and associated diseases. Innate Lymphoid Cells are generally regarded as tissue resident and early responders, while conversely within the central nervous system at steady-state their presence is limited. This review describes the current understandings on Innate Lymphoid Cells in the central nervous system at steady-state and its borders plus their involvement in major neurological diseases like ischemic stroke, Alzheimer’s disease and Multiple Sclerosis.https://www.frontiersin.org/articles/10.3389/fimmu.2022.837250/fullNKILC1ILC2ILC3ischemic strokeAlzheimer’s disease |
| spellingShingle | Shuaiwei Wang Serge A. van de Pavert Innate Lymphoid Cells in the Central Nervous System Frontiers in Immunology NK ILC1 ILC2 ILC3 ischemic stroke Alzheimer’s disease |
| title | Innate Lymphoid Cells in the Central Nervous System |
| title_full | Innate Lymphoid Cells in the Central Nervous System |
| title_fullStr | Innate Lymphoid Cells in the Central Nervous System |
| title_full_unstemmed | Innate Lymphoid Cells in the Central Nervous System |
| title_short | Innate Lymphoid Cells in the Central Nervous System |
| title_sort | innate lymphoid cells in the central nervous system |
| topic | NK ILC1 ILC2 ILC3 ischemic stroke Alzheimer’s disease |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.837250/full |
| work_keys_str_mv | AT shuaiweiwang innatelymphoidcellsinthecentralnervoussystem AT sergeavandepavert innatelymphoidcellsinthecentralnervoussystem |