A review of the role of Haemophilus influenzae in community-acquired pneumonia

<p class="Paragraph">In an era when <em>Haemophilus influenzae</em> type b (Hib) conjugate vaccine is widely used, the incidence of Hib as a cause of community-acquired pneumonia (CAP) has dramatically declined. Non-typeable <em>H. influenzae</em> (NTHi) strai...

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Bibliographic Details
Main Author: Mary PE Slack
Format: Article
Language:English
Published: BMC 2015-01-01
Series:Pneumonia
Subjects:
Online Access:https://pneumonia.org.au/index.php/pneumonia/article/view/520
Description
Summary:<p class="Paragraph">In an era when <em>Haemophilus influenzae</em> type b (Hib) conjugate vaccine is widely used, the incidence of Hib as a cause of community-acquired pneumonia (CAP) has dramatically declined. Non-typeable <em>H. influenzae</em> (NTHi) strains and, occasionally, other encapsulated serotypes of <em>H. influenzae</em> are now the cause of the majority of invasive <em>H. influenzae</em> infections, including bacteraemic CAP. NTHi have long been recognised as an important cause of lower respiratory tract infection, including pneumonia, in adults, especially those with underlying diseases. The role of NTHi as a cause of non-bacteraemic CAP in children is less clear. In this review the evidence for the role of NTHi and capsulated strains of <em>H. influenzae</em> will be examined.</p><p> </p>
ISSN:2200-6133