Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal Anesthesia
Background: Inadequate pain control has a significant role in maternal and neonatal health in the early postpartum period. It interferes with breastfeeding and has a negative influence on child normal growth. This study aimed to evaluate the preemptive effect of intraincisional infiltration magnesiu...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2017-12-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/7976 |
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| author | Mitra Jabalameli Seyed Mahmood Hashemian Azar Danesh-Shahraki Mansoureh Zarin-Makan |
| author_facet | Mitra Jabalameli Seyed Mahmood Hashemian Azar Danesh-Shahraki Mansoureh Zarin-Makan |
| author_sort | Mitra Jabalameli |
| collection | DOAJ |
| description | Background: Inadequate pain control has a significant role in maternal and neonatal health in the early postpartum period. It interferes with breastfeeding and has a negative influence on child normal growth. This study aimed to evaluate the preemptive effect of intraincisional infiltration magnesium sulfate on postoperative pain control.
Methods: This was a double-blind randomized prospective clinical trial study involving 64 pregnant women underwent cesarean section, from 2015 to 2016, in Shahid Beheshti and Alzahra hospitals, Isfahan, Iran. Patients were randomly assigned to two equal groups. Patients in the case group received 1 mg of magnesium sulfate in the incisional site. Pethidine was a pain reliever in the follow-up examination. The obtained data, including mean pain intensity, nausea and vomiting, pethidine consumption, blood pressure, heart rate, sedation score, and patient satisfaction were collected and analyzed using repeated measures ANOVA and Man-Whitney tests.
Findings: Mean pethidine consumption was not statistically different between two groups (P = 0.850). Mean pain intensity was significantly different only 12 (P = 0.024) and 24 (P = 0.007) hours after the surgery and it was not significant at other time points (P = 0.130). Other parameters were also not statistically significant.
Conclusion: It seems that preemptive intraincisional infiltration of magnesium sulfate could not have a significant effect on postoperative pain and reduction of pethidine use in cesarean section. |
| first_indexed | 2024-03-12T08:14:16Z |
| format | Article |
| id | doaj.art-c7a83f5b566a4c2bb5a13f62fabd0403 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T08:14:16Z |
| publishDate | 2017-12-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-c7a83f5b566a4c2bb5a13f62fabd04032023-09-02T19:01:18ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2017-12-0135450140514112662Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal AnesthesiaMitra Jabalameli0Seyed Mahmood Hashemian1Azar Danesh-Shahraki2Mansoureh Zarin-Makan3Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranStudent of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranNurse, Shahid Beheshti Hospital, Isfahan University of Medical Sciences, Isfahan, IranBackground: Inadequate pain control has a significant role in maternal and neonatal health in the early postpartum period. It interferes with breastfeeding and has a negative influence on child normal growth. This study aimed to evaluate the preemptive effect of intraincisional infiltration magnesium sulfate on postoperative pain control. Methods: This was a double-blind randomized prospective clinical trial study involving 64 pregnant women underwent cesarean section, from 2015 to 2016, in Shahid Beheshti and Alzahra hospitals, Isfahan, Iran. Patients were randomly assigned to two equal groups. Patients in the case group received 1 mg of magnesium sulfate in the incisional site. Pethidine was a pain reliever in the follow-up examination. The obtained data, including mean pain intensity, nausea and vomiting, pethidine consumption, blood pressure, heart rate, sedation score, and patient satisfaction were collected and analyzed using repeated measures ANOVA and Man-Whitney tests. Findings: Mean pethidine consumption was not statistically different between two groups (P = 0.850). Mean pain intensity was significantly different only 12 (P = 0.024) and 24 (P = 0.007) hours after the surgery and it was not significant at other time points (P = 0.130). Other parameters were also not statistically significant. Conclusion: It seems that preemptive intraincisional infiltration of magnesium sulfate could not have a significant effect on postoperative pain and reduction of pethidine use in cesarean section.http://jims.mui.ac.ir/index.php/jims/article/view/7976Cesarean sectionMagnesium sulfatePainPethidine |
| spellingShingle | Mitra Jabalameli Seyed Mahmood Hashemian Azar Danesh-Shahraki Mansoureh Zarin-Makan Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal Anesthesia مجله دانشکده پزشکی اصفهان Cesarean section Magnesium sulfate Pain Pethidine |
| title | Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal Anesthesia |
| title_full | Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal Anesthesia |
| title_fullStr | Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal Anesthesia |
| title_full_unstemmed | Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal Anesthesia |
| title_short | Evaluating the Efficacy of Preemptive Intraincisional Infiltration of Magnesium Sulfate on Postoperative Pain in Cesarean Section under Spinal Anesthesia |
| title_sort | evaluating the efficacy of preemptive intraincisional infiltration of magnesium sulfate on postoperative pain in cesarean section under spinal anesthesia |
| topic | Cesarean section Magnesium sulfate Pain Pethidine |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/7976 |
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