Immune activation and inflammation in lactating women on combination antiretroviral therapy: role of gut dysfunction and gut microbiota imbalance

Immune activation and inflammation in lactating women on combination antiretroviral therapy: role of gut dysfunction and gut microbiota imbalance

IntroductionCombination antiretroviral therapy (cART) effectively controls HIV; however, chronic low-level viremia and gut microbiota dysbiosis remain significant drivers of gut and systemic inflammation. In this study, we explored the relationship between gut microbiota composition, intestinal infl...

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Bibliographic Details
Main Authors: Privilege Tendai Munjoma, Panashe Chandiwana, Jacqueline Wyss, Arthur John Mazhandu, Sebastian Bruno Ulrich Jordi, Rutendo Gutsire, Leolin Katsidzira, Bahtiyar Yilmaz, Benjamin Misselwitz, Kerina Duri
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
fecal calprotectin
microbial translocation
systemic inflammation
HIV
gut microbiota
lactating women
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1280262/full

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