A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines
Abstract We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH2OH·HCl and NaIO4. We found that the same combination of NH2OH·HCl and NaIO4 is also very effective for nucleophilic ring opening of aziridines.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2017-03-01
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| Series: | SynOpen |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1588809 |
| _version_ | 1828303496068202496 |
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| author | Nirnita Chakraborty Ghosal Sachinta Mahato Rana Chatterjee Sougata Santra Grigory V. Zyryanov Adinath Majee |
| author_facet | Nirnita Chakraborty Ghosal Sachinta Mahato Rana Chatterjee Sougata Santra Grigory V. Zyryanov Adinath Majee |
| author_sort | Nirnita Chakraborty Ghosal |
| collection | DOAJ |
| description | Abstract
We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH2OH·HCl and NaIO4. We found that the same combination of NH2OH·HCl and NaIO4 is also very effective for nucleophilic ring opening of aziridines. |
| first_indexed | 2024-04-13T13:54:50Z |
| format | Article |
| id | doaj.art-c7abbf2fa8034ecfbd2f846fe4ef9f58 |
| institution | Directory Open Access Journal |
| issn | 2509-9396 |
| language | English |
| last_indexed | 2024-04-13T13:54:50Z |
| publishDate | 2017-03-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | SynOpen |
| spelling | doaj.art-c7abbf2fa8034ecfbd2f846fe4ef9f582022-12-22T02:44:14ZengGeorg Thieme Verlag KGSynOpen2509-93962017-03-0101010015002310.1055/s-0036-1588809A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of AziridinesNirnita Chakraborty Ghosal0Sachinta Mahato1Rana Chatterjee2Sougata Santra3Grigory V. Zyryanov4Adinath Majee5Department of Chemistry, Visva-Bharati (A Central University)Department of Chemistry, Visva-Bharati (A Central University)Department of Chemistry, Visva-Bharati (A Central University)Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal UniversityDepartment of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal UniversityDepartment of Chemistry, Visva-Bharati (A Central University)Abstract We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH2OH·HCl and NaIO4. We found that the same combination of NH2OH·HCl and NaIO4 is also very effective for nucleophilic ring opening of aziridines.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1588809aziridinesdifunctionalizationaminoiodidein situ generated iodineroom temperature |
| spellingShingle | Nirnita Chakraborty Ghosal Sachinta Mahato Rana Chatterjee Sougata Santra Grigory V. Zyryanov Adinath Majee A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines SynOpen aziridines difunctionalization aminoiodide in situ generated iodine room temperature |
| title | A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines |
| title_full | A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines |
| title_fullStr | A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines |
| title_full_unstemmed | A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines |
| title_short | A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines |
| title_sort | mild and efficient method for the syntheses and regioselective ring opening of aziridines |
| topic | aziridines difunctionalization aminoiodide in situ generated iodine room temperature |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1588809 |
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