Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulation

Background: Simulation of tomographic imaging systems with fan-beam geometry, estimation of scattered beam profile using Monte Carlo techniques, and scatter correction using estimated data have always been new challenges in the field of medical imaging. The most important aspect is to ensure the res...

Full description

Bibliographic Details
Main Authors: Iman Azinkhah, Mahdi Sadeghi, Peyman Sheikhzadeh, Malakeh Malekzadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Medical Signals and Sensors
Subjects:
Online Access:http://www.jmssjournal.net/article.asp?issn=2228-7477;year=2023;volume=13;issue=4;spage=280;epage=289;aulast=Azinkhah
_version_ 1797645598221926400
author Iman Azinkhah
Mahdi Sadeghi
Peyman Sheikhzadeh
Malakeh Malekzadeh
author_facet Iman Azinkhah
Mahdi Sadeghi
Peyman Sheikhzadeh
Malakeh Malekzadeh
author_sort Iman Azinkhah
collection DOAJ
description Background: Simulation of tomographic imaging systems with fan-beam geometry, estimation of scattered beam profile using Monte Carlo techniques, and scatter correction using estimated data have always been new challenges in the field of medical imaging. The most important aspect is to ensure the results of the simulation and the accuracy of the scatter correction. This study aims to simulate 128-slice computed tomography (CT) scan using the Geant4 Application for Tomographic Emission (GATE) program, to assess the validity of this simulation and estimate the scatter profile. Finally, a quantitative comparison of the results is made from scatter correction. Methods: In this study, 128-slice CT scan devices with fan-beam geometry along with two phantoms were simulated by GATE program. Two validation methods were performed to validate the simulation results. The data obtained from scatter estimation of the simulation was used in a projection-based scatter correction technique, and the post-correction results were analyzed using four quantities, such as: pixel intensity, CT number inaccuracy, contrast-to-noise ratio (CNR), and signal-to-noise ratio (SNR). Results: Both validation methods have confirmed the appropriate accuracy of the simulation. In the quantitative analysis of the results before and after the scatter correction, it should be said that the pixel intensity patterns were close to each other, and the accuracy of the CT scan number reached <10%. Moreover, CNR and SNR have increased by more than 30%–65% respectively in all studied areas. Conclusion: The comparison of the results before and after scatter correction shows an improvement in CNR and SNR while a reduction in cupping artifact according to pixel intensity pattern and enhanced CT number accuracy.
first_indexed 2024-03-11T14:49:08Z
format Article
id doaj.art-c7ac275eb9fc4cb6a614fcd3a38e163c
institution Directory Open Access Journal
issn 2228-7477
language English
last_indexed 2024-03-11T14:49:08Z
publishDate 2023-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Medical Signals and Sensors
spelling doaj.art-c7ac275eb9fc4cb6a614fcd3a38e163c2023-10-30T10:30:07ZengWolters Kluwer Medknow PublicationsJournal of Medical Signals and Sensors2228-74772023-01-0113428028910.4103/jmss.jmss_71_22Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulationIman AzinkhahMahdi SadeghiPeyman SheikhzadehMalakeh MalekzadehBackground: Simulation of tomographic imaging systems with fan-beam geometry, estimation of scattered beam profile using Monte Carlo techniques, and scatter correction using estimated data have always been new challenges in the field of medical imaging. The most important aspect is to ensure the results of the simulation and the accuracy of the scatter correction. This study aims to simulate 128-slice computed tomography (CT) scan using the Geant4 Application for Tomographic Emission (GATE) program, to assess the validity of this simulation and estimate the scatter profile. Finally, a quantitative comparison of the results is made from scatter correction. Methods: In this study, 128-slice CT scan devices with fan-beam geometry along with two phantoms were simulated by GATE program. Two validation methods were performed to validate the simulation results. The data obtained from scatter estimation of the simulation was used in a projection-based scatter correction technique, and the post-correction results were analyzed using four quantities, such as: pixel intensity, CT number inaccuracy, contrast-to-noise ratio (CNR), and signal-to-noise ratio (SNR). Results: Both validation methods have confirmed the appropriate accuracy of the simulation. In the quantitative analysis of the results before and after the scatter correction, it should be said that the pixel intensity patterns were close to each other, and the accuracy of the CT scan number reached <10%. Moreover, CNR and SNR have increased by more than 30%–65% respectively in all studied areas. Conclusion: The comparison of the results before and after scatter correction shows an improvement in CNR and SNR while a reduction in cupping artifact according to pixel intensity pattern and enhanced CT number accuracy.http://www.jmssjournal.net/article.asp?issn=2228-7477;year=2023;volume=13;issue=4;spage=280;epage=289;aulast=Azinkhahcorrectioncomputed tomographygeant4 application for tomographic emissionscatter
spellingShingle Iman Azinkhah
Mahdi Sadeghi
Peyman Sheikhzadeh
Malakeh Malekzadeh
Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulation
Journal of Medical Signals and Sensors
correction
computed tomography
geant4 application for tomographic emission
scatter
title Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulation
title_full Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulation
title_fullStr Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulation
title_full_unstemmed Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulation
title_short Quantitative evaluation of scatter correction in 128-slice fan-beam computed tomography scan using geant4 application for tomographic emission Monte Carlo simulation
title_sort quantitative evaluation of scatter correction in 128 slice fan beam computed tomography scan using geant4 application for tomographic emission monte carlo simulation
topic correction
computed tomography
geant4 application for tomographic emission
scatter
url http://www.jmssjournal.net/article.asp?issn=2228-7477;year=2023;volume=13;issue=4;spage=280;epage=289;aulast=Azinkhah
work_keys_str_mv AT imanazinkhah quantitativeevaluationofscattercorrectionin128slicefanbeamcomputedtomographyscanusinggeant4applicationfortomographicemissionmontecarlosimulation
AT mahdisadeghi quantitativeevaluationofscattercorrectionin128slicefanbeamcomputedtomographyscanusinggeant4applicationfortomographicemissionmontecarlosimulation
AT peymansheikhzadeh quantitativeevaluationofscattercorrectionin128slicefanbeamcomputedtomographyscanusinggeant4applicationfortomographicemissionmontecarlosimulation
AT malakehmalekzadeh quantitativeevaluationofscattercorrectionin128slicefanbeamcomputedtomographyscanusinggeant4applicationfortomographicemissionmontecarlosimulation