The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial
To evaluate the effect of pre-emptive dose of intravenous ketamine on Oculocardiac reflex (OCR) in pediatric strabismus surgery. 60 children with age between 2 to 8 years old candidate for strabismus surgery were randomly divided into two groups of 30 participants. After induction of anesthesia, in...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2019-09-01
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| Series: | Acta Medica Iranica |
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| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/7741 |
| _version_ | 1818834667770478592 |
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| author | Mehrdad Goudarzi Mohammad Mehrpour Mohammad Saleh Rajabi Mehdi Sanatkar Ebrahim Espahbodi Mohammad Reza Akbari |
| author_facet | Mehrdad Goudarzi Mohammad Mehrpour Mohammad Saleh Rajabi Mehdi Sanatkar Ebrahim Espahbodi Mohammad Reza Akbari |
| author_sort | Mehrdad Goudarzi |
| collection | DOAJ |
| description | To evaluate the effect of pre-emptive dose of intravenous ketamine on Oculocardiac reflex (OCR) in pediatric strabismus surgery. 60 children with age between 2 to 8 years old candidate for strabismus surgery were randomly divided into two groups of 30 participants. After induction of anesthesia, in one group, pre-emptive dose of ketamine (0.15 mg/kg) was given intravenously (ketamine group), while the other group was given the same volume of normal saline (control group). During the surgery, OCR was recorded if the heart rate had decreased 20% or more from the baseline. In the recovery room, the incidence of nausea and vomiting, bronchospasm, laryngospasm, hallucination and recovery nurse satisfaction score were recorded. The incidence of OCR in total participants was 31 (51.7%). In control group 21 (70%) patients had OCR during surgery while this incidence was 10 (33.3%) in ketamine group which was significantly lower (P:0.004). the incidence of postoperative nausea and vomiting and the mean of recovery nurse satisfaction score in recovery room were not significantly different between two groups. The hallucination was not seen in any cases of two groups after surgery. The pre-emptive dose of ketamine (0.15 mg/kg) can reduce incidence of OCR in the pediatric strabismus surgery. |
| first_indexed | 2024-12-19T02:38:28Z |
| format | Article |
| id | doaj.art-c7ae897723f745338e2ff669bceb25da |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-12-19T02:38:28Z |
| publishDate | 2019-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-c7ae897723f745338e2ff669bceb25da2022-12-21T20:39:15ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942019-09-0157510.18502/acta.v57i5.18647741The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical TrialMehrdad Goudarzi0Mohammad Mehrpour1Mohammad Saleh Rajabi2Mehdi Sanatkar3Ebrahim Espahbodi4Mohammad Reza Akbari5Department of Anesthesiology and Critical Care, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology and Critical Care, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology and Critical Care, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.To evaluate the effect of pre-emptive dose of intravenous ketamine on Oculocardiac reflex (OCR) in pediatric strabismus surgery. 60 children with age between 2 to 8 years old candidate for strabismus surgery were randomly divided into two groups of 30 participants. After induction of anesthesia, in one group, pre-emptive dose of ketamine (0.15 mg/kg) was given intravenously (ketamine group), while the other group was given the same volume of normal saline (control group). During the surgery, OCR was recorded if the heart rate had decreased 20% or more from the baseline. In the recovery room, the incidence of nausea and vomiting, bronchospasm, laryngospasm, hallucination and recovery nurse satisfaction score were recorded. The incidence of OCR in total participants was 31 (51.7%). In control group 21 (70%) patients had OCR during surgery while this incidence was 10 (33.3%) in ketamine group which was significantly lower (P:0.004). the incidence of postoperative nausea and vomiting and the mean of recovery nurse satisfaction score in recovery room were not significantly different between two groups. The hallucination was not seen in any cases of two groups after surgery. The pre-emptive dose of ketamine (0.15 mg/kg) can reduce incidence of OCR in the pediatric strabismus surgery.https://acta.tums.ac.ir/index.php/acta/article/view/7741Oculocardiac reflexKetamineStrabismusPediatric |
| spellingShingle | Mehrdad Goudarzi Mohammad Mehrpour Mohammad Saleh Rajabi Mehdi Sanatkar Ebrahim Espahbodi Mohammad Reza Akbari The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial Acta Medica Iranica Oculocardiac reflex Ketamine Strabismus Pediatric |
| title | The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial |
| title_full | The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial |
| title_fullStr | The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial |
| title_full_unstemmed | The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial |
| title_short | The Effect of Pre-Emptive Dose of Intravenous Ketamine on Oculocardiac Reflex in Pediatric Strabismus Surgery: A Randomized Clinical Trial |
| title_sort | effect of pre emptive dose of intravenous ketamine on oculocardiac reflex in pediatric strabismus surgery a randomized clinical trial |
| topic | Oculocardiac reflex Ketamine Strabismus Pediatric |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/7741 |
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