Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth
Background/purpose: ProRoot MTA, Vitapex, and Metapex are widely used for pulp treatment of primary tooth. The aim of this study was to compare the pulpal responses to ProRoot MTA, Vitapex, and Metapex in a canine model of pulpotomy. Materials and methods: Pulpotomy procedure was performed to 34 tee...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-10-01
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| Series: | Journal of Dental Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1991790220302889 |
| _version_ | 1819083669340422144 |
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| author | Woojin Kwon Ik-Hwan Kim Chung-Min Kang Byurira Kim Yooseok Shin Je Seon Song |
| author_facet | Woojin Kwon Ik-Hwan Kim Chung-Min Kang Byurira Kim Yooseok Shin Je Seon Song |
| author_sort | Woojin Kwon |
| collection | DOAJ |
| description | Background/purpose: ProRoot MTA, Vitapex, and Metapex are widely used for pulp treatment of primary tooth. The aim of this study was to compare the pulpal responses to ProRoot MTA, Vitapex, and Metapex in a canine model of pulpotomy. Materials and methods: Pulpotomy procedure was performed to 34 teeth (21 incisors and 13 premolars) and ProRoot MTA, Vitapex or Metapex was applicated to artificially exposed pulp tissues. After 13 weeks, the teeth were extracted and processed with hematoxylin-eosin staining for histologic evaluation. All specimens were evaluated in several categorys related to calcific barrier, inflammatory responses and the area of calcific barrier formation was measured. Results: Most of the specimens in the ProRoot MTA group developed a calcific barrier at the pulp amputation site and showed a low level of inflammatory response. However, in comparison to ProRoot MTA group, a small amount of calcific barrier formed in Vitapex and Metapex groups. Conclusion: This in vivo study found that Vitapex and Metapex induced similar pulpal responses but showed poor outcomes compared with using ProRoot MTA. Vitapex and Metapex are therefore not good substitutes for ProRoot MTA in direct pulp capping and pulpotomy. |
| first_indexed | 2024-12-21T20:36:14Z |
| format | Article |
| id | doaj.art-c7afce8e77d649eb87b3e161e63affd6 |
| institution | Directory Open Access Journal |
| issn | 1991-7902 |
| language | English |
| last_indexed | 2024-12-21T20:36:14Z |
| publishDate | 2021-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Dental Sciences |
| spelling | doaj.art-c7afce8e77d649eb87b3e161e63affd62022-12-21T18:51:05ZengElsevierJournal of Dental Sciences1991-79022021-10-0116412741280Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teethWoojin Kwon0Ik-Hwan Kim1Chung-Min Kang2Byurira Kim3Yooseok Shin4Je Seon Song5Department of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of KoreaDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of KoreaDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of KoreaDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of KoreaOral Science Research Center, College of Dentistry, Yonsei University, Seoul, Republic of Korea; Department of Conservative Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of KoreaDepartment of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul, Republic of Korea; Oral Science Research Center, College of Dentistry, Yonsei University, Seoul, Republic of Korea; Corresponding author. Department of Pediatric Dentistry, College of Dentistry, Yonsei University, Seoul, 03722, Republic of Korea.Background/purpose: ProRoot MTA, Vitapex, and Metapex are widely used for pulp treatment of primary tooth. The aim of this study was to compare the pulpal responses to ProRoot MTA, Vitapex, and Metapex in a canine model of pulpotomy. Materials and methods: Pulpotomy procedure was performed to 34 teeth (21 incisors and 13 premolars) and ProRoot MTA, Vitapex or Metapex was applicated to artificially exposed pulp tissues. After 13 weeks, the teeth were extracted and processed with hematoxylin-eosin staining for histologic evaluation. All specimens were evaluated in several categorys related to calcific barrier, inflammatory responses and the area of calcific barrier formation was measured. Results: Most of the specimens in the ProRoot MTA group developed a calcific barrier at the pulp amputation site and showed a low level of inflammatory response. However, in comparison to ProRoot MTA group, a small amount of calcific barrier formed in Vitapex and Metapex groups. Conclusion: This in vivo study found that Vitapex and Metapex induced similar pulpal responses but showed poor outcomes compared with using ProRoot MTA. Vitapex and Metapex are therefore not good substitutes for ProRoot MTA in direct pulp capping and pulpotomy.http://www.sciencedirect.com/science/article/pii/S1991790220302889ProRoot MTAVitapexMetapexPulpal response |
| spellingShingle | Woojin Kwon Ik-Hwan Kim Chung-Min Kang Byurira Kim Yooseok Shin Je Seon Song Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth Journal of Dental Sciences ProRoot MTA Vitapex Metapex Pulpal response |
| title | Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth |
| title_full | Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth |
| title_fullStr | Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth |
| title_full_unstemmed | Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth |
| title_short | Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth |
| title_sort | comparative study of pulpal responses to proroot mta vitapex and metapex in canine teeth |
| topic | ProRoot MTA Vitapex Metapex Pulpal response |
| url | http://www.sciencedirect.com/science/article/pii/S1991790220302889 |
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