Melanotic neuroectodermal tumor of infancy: Presentation of a case

The melanotic neuroectodermal tumor of infancy (MNTI) is a fairly rare, benign, pigmented lesion with a rapid expansile growth and a high recurrence rate that commonly occurs in the anterior maxilla of infants younger than 1 year and mainly in the first 6 months of life. Microscopically, large polyg...

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Main Authors: Narendra Nath Singh, Manpreet Singh, Gadiputi Sreedhar, Pallav Singhal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:SRM Journal of Research in Dental Sciences
Subjects:
Online Access:http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=2;spage=123;epage=126;aulast=Singh
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author Narendra Nath Singh
Manpreet Singh
Gadiputi Sreedhar
Pallav Singhal
author_facet Narendra Nath Singh
Manpreet Singh
Gadiputi Sreedhar
Pallav Singhal
author_sort Narendra Nath Singh
collection DOAJ
description The melanotic neuroectodermal tumor of infancy (MNTI) is a fairly rare, benign, pigmented lesion with a rapid expansile growth and a high recurrence rate that commonly occurs in the anterior maxilla of infants younger than 1 year and mainly in the first 6 months of life. Microscopically, large polygonal epithelioid cells resembling melanocytes, with variable deposits of melanin, and smaller neuroblast-like round cells characterize MNTI. Malignant transformation may occur. The tumor was first described by Krompecher in 1918 as a congenital melanocarcinoma. In 1992, the designation "MNTI" was accepted by and used in the World Health Organization classification of odontogenic tumors. One such case was diagnosed in the department of oral pathology and microbiology and is presented.
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spelling doaj.art-c7afddabff304129bb6d72450847fd972022-12-22T04:23:40ZengWolters Kluwer Medknow PublicationsSRM Journal of Research in Dental Sciences2772-52432772-52512014-01-015212312610.4103/0976-433X.132089Melanotic neuroectodermal tumor of infancy: Presentation of a caseNarendra Nath SinghManpreet SinghGadiputi SreedharPallav SinghalThe melanotic neuroectodermal tumor of infancy (MNTI) is a fairly rare, benign, pigmented lesion with a rapid expansile growth and a high recurrence rate that commonly occurs in the anterior maxilla of infants younger than 1 year and mainly in the first 6 months of life. Microscopically, large polygonal epithelioid cells resembling melanocytes, with variable deposits of melanin, and smaller neuroblast-like round cells characterize MNTI. Malignant transformation may occur. The tumor was first described by Krompecher in 1918 as a congenital melanocarcinoma. In 1992, the designation "MNTI" was accepted by and used in the World Health Organization classification of odontogenic tumors. One such case was diagnosed in the department of oral pathology and microbiology and is presented.http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=2;spage=123;epage=126;aulast=Singhbenigndiagnosismaxillamelanotic neuroectodermal tumor of infancyodontogenic tumors
spellingShingle Narendra Nath Singh
Manpreet Singh
Gadiputi Sreedhar
Pallav Singhal
Melanotic neuroectodermal tumor of infancy: Presentation of a case
SRM Journal of Research in Dental Sciences
benign
diagnosis
maxilla
melanotic neuroectodermal tumor of infancy
odontogenic tumors
title Melanotic neuroectodermal tumor of infancy: Presentation of a case
title_full Melanotic neuroectodermal tumor of infancy: Presentation of a case
title_fullStr Melanotic neuroectodermal tumor of infancy: Presentation of a case
title_full_unstemmed Melanotic neuroectodermal tumor of infancy: Presentation of a case
title_short Melanotic neuroectodermal tumor of infancy: Presentation of a case
title_sort melanotic neuroectodermal tumor of infancy presentation of a case
topic benign
diagnosis
maxilla
melanotic neuroectodermal tumor of infancy
odontogenic tumors
url http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=2;spage=123;epage=126;aulast=Singh
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AT manpreetsingh melanoticneuroectodermaltumorofinfancypresentationofacase
AT gadiputisreedhar melanoticneuroectodermaltumorofinfancypresentationofacase
AT pallavsinghal melanoticneuroectodermaltumorofinfancypresentationofacase