Cells on Hydrogels with Micron-Scaled Stiffness Patterns Demonstrate Local Stiffness Sensing

Cells on Hydrogels with Micron-Scaled Stiffness Patterns Demonstrate Local Stiffness Sensing

Cell rigidity sensing—a basic cellular process allowing cells to adapt to mechanical cues—involves cell capabilities exerting force on the extracellular environment. In vivo, cells are exposed to multi-scaled heterogeneities in the mechanical properties of the surroundings. Here, we investigate whet...

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Bibliographic Details
Main Authors: Abbas Mgharbel, Camille Migdal, Nicolas Bouchonville, Paul Dupenloup, David Fuard, Eline Lopez-Soler, Caterina Tomba, Marie Courçon, Danielle Gulino-Debrac, Héléne Delanoë-Ayari, Alice Nicolas
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Nanomaterials
Subjects:
stiffness patterning
gray-leveled lithography
traction force microscopy
hydrogel
cell ADHESION
mechanosensitivity
Online Access:https://www.mdpi.com/2079-4991/12/4/648

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https://www.mdpi.com/2079-4991/12/4/648

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