Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications
Carbonated hydroxyapatite (CHAP)-doped with different concentrations of gold (Au) was sputtered on a scaffold of alumina via pulsed laser deposition technique. The structural, microstructural and morphological behaviors were investigated. FESEM indicated that Au-CHAP was formed as spherical shapes w...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-07-01
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| Series: | Journal of Materials Research and Technology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785420314083 |
| _version_ | 1818213778147246080 |
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| author | M.K. Ahmed Rania Ramadan M. Afifi A.A. Menazea |
| author_facet | M.K. Ahmed Rania Ramadan M. Afifi A.A. Menazea |
| author_sort | M.K. Ahmed |
| collection | DOAJ |
| description | Carbonated hydroxyapatite (CHAP)-doped with different concentrations of gold (Au) was sputtered on a scaffold of alumina via pulsed laser deposition technique. The structural, microstructural and morphological behaviors were investigated. FESEM indicated that Au-CHAP was formed as spherical shapes with diameters around 0.25–0.45 μm, while alumina was formed in rectangular grains with dimensions around 0.9 × 1.3 × 2.25 μm3. The examination of mechanical properties indicated that micro-hardness has been enhanced with a variation of sputtering composition upon changing of Au concentration. It was enhanced form 31.0 GPa at zero contribution of Au to be 34.0 GPa at the highest one. Moreover, the cell viability and cells were grown on the scaffold surface were also examined against the HFB4 cell line. It was shown that scaffold compositions displayed high compatibility and reached 92.5 ± 4.7%. Furthermore, the cells were not only spread and grew on the scaffold's surface, but they also proliferated deeply through the porosity of the scaffold as a function of Au dopant. This implies that tailoring scaffold for biomedical engineering depends on superfine composition could be suggested for numerous applications. |
| first_indexed | 2024-12-12T06:09:41Z |
| format | Article |
| id | doaj.art-c7b3bc7b41044e2391d6bfef340abc3c |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2024-12-12T06:09:41Z |
| publishDate | 2020-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-c7b3bc7b41044e2391d6bfef340abc3c2022-12-22T00:35:11ZengElsevierJournal of Materials Research and Technology2238-78542020-07-019488548866Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applicationsM.K. Ahmed0Rania Ramadan1M. Afifi2A.A. Menazea3Department of Physics, Faculty of Science, Suez University, Suez, EgyptMaterials Science Lab (1), Physics Department, Faculty of Science, Cairo University, Giza, EgyptUltrasonic Laboratory, National Institute of Standards, Giza, Egypt; Corresponding author.Laser Technology Unit, National Research Centre, Dokki 12622 Giza, Egypt; Spectroscopy Department, Physics Division, National Research Centre, Dokki 12622 Giza, EgyptCarbonated hydroxyapatite (CHAP)-doped with different concentrations of gold (Au) was sputtered on a scaffold of alumina via pulsed laser deposition technique. The structural, microstructural and morphological behaviors were investigated. FESEM indicated that Au-CHAP was formed as spherical shapes with diameters around 0.25–0.45 μm, while alumina was formed in rectangular grains with dimensions around 0.9 × 1.3 × 2.25 μm3. The examination of mechanical properties indicated that micro-hardness has been enhanced with a variation of sputtering composition upon changing of Au concentration. It was enhanced form 31.0 GPa at zero contribution of Au to be 34.0 GPa at the highest one. Moreover, the cell viability and cells were grown on the scaffold surface were also examined against the HFB4 cell line. It was shown that scaffold compositions displayed high compatibility and reached 92.5 ± 4.7%. Furthermore, the cells were not only spread and grew on the scaffold's surface, but they also proliferated deeply through the porosity of the scaffold as a function of Au dopant. This implies that tailoring scaffold for biomedical engineering depends on superfine composition could be suggested for numerous applications.http://www.sciencedirect.com/science/article/pii/S2238785420314083AluminaAuHydroxyapatitePulsed laser depositionOrthopedic |
| spellingShingle | M.K. Ahmed Rania Ramadan M. Afifi A.A. Menazea Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications Journal of Materials Research and Technology Alumina Au Hydroxyapatite Pulsed laser deposition Orthopedic |
| title | Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications |
| title_full | Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications |
| title_fullStr | Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications |
| title_full_unstemmed | Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications |
| title_short | Au-doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications |
| title_sort | au doped carbonated hydroxyapatite sputtered on alumina scaffolds via pulsed laser deposition for biomedical applications |
| topic | Alumina Au Hydroxyapatite Pulsed laser deposition Orthopedic |
| url | http://www.sciencedirect.com/science/article/pii/S2238785420314083 |
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