YB-1 transferred by gastric cancer exosomes promotes angiogenesis via enhancing the expression of angiogenic factors in vascular endothelial cells

YB-1 transferred by gastric cancer exosomes promotes angiogenesis via enhancing the expression of angiogenic factors in vascular endothelial cells

Abstract Background Angiogenesis is important for the progression of gastric cancer (GC). Y-box binding protein 1 (YB-1) predicts advanced disease and indicates neovasculature formation in GC tissues, while the related mechanisms remain elusive. Exosomes mediate intercellular communications via tran...

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Bibliographic Details
Main Authors: Xiaoxia Xue, Jin Huang, Kai Yu, Xinyue Chen, Yini He, Dianjun Qi, Ying Wu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
YB-1
Exosome
Gastric cancer
Angiogenesis
IL-8
VEGF
Online Access:http://link.springer.com/article/10.1186/s12885-020-07509-6

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