Patient Characteristics Influence Activated Signal Transducer and Activator of Transcription 3 (STAT3) Levels in Primary Breast Cancer—Impact on Prognosis

Patient Characteristics Influence Activated Signal Transducer and Activator of Transcription 3 (STAT3) Levels in Primary Breast Cancer—Impact on Prognosis

Background: Activated signal transducer and activator of transcription 3 (pSTAT3) is often present in breast cancer, but its prognostic impact is still unclear. We investigated how breast tumor-specific pSTAT3Y705 levels are associated with patient and tumor characteristics and risk of recurrence.Ma...

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Bibliographic Details
Main Authors: Linn Nilsson, Emma Sandén, Somayeh Khazaei, Helga Tryggvadottir, Björn Nodin, Karin Jirström, Signe Borgquist, Karolin Isaksson, Helena Jernström
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Oncology
Subjects:
signal transducer and activator of transcription 3 (STAT3)
breast cancer
prognosis
immunohistochemistry
tamoxifen
lifestyle
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01278/full

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