Parental exposure to propiconazole at environmentally relevant concentrations induces thyroid and metabolism disruption in zebrafish (Danio rerio) offspring: An in vivo, in silico and in vitro study

Parental exposure to propiconazole at environmentally relevant concentrations induces thyroid and metabolism disruption in zebrafish (Danio rerio) offspring: An in vivo, in silico and in vitro study

Propiconazole is used against fungal growth in agriculture and is released into the environment, but is a potential health threat to aquatic organisms. Propiconazole induces a generational effect on zebrafish, although the toxic mechanisms involved have not been described. The aim of this study was...

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Bibliographic Details
Main Authors: Miaomiao Teng, Wentian Zhao, Xiangguang Chen, Chen Wang, Lingfeng Zhou, Chengju Wang, Yong Xu
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Propiconazole
Metabolomics
Zebrafish
HPT axis
in vitro
in silico
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322007059

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