HIF-1α Pulmonary Phenotype Wide Association Study Unveils a Link to Inflammatory Airway Conditions

HIF-1α Pulmonary Phenotype Wide Association Study Unveils a Link to Inflammatory Airway Conditions

Despite experimental data linking HIF-1α dysfunction to inflammatory airway conditions, the effect of single nucleotide polymorphisms within the HIF1A gene on these conditions remains poorly understood. In the current study, we complete a phenotype wide association study to assess the link between S...

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Bibliographic Details
Main Authors: Jelte Kelchtermans, Xiao Chang, Michael E. March, Frank Mentch, Patrick M. A. Sleiman, Hakon Hakonarson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
phenotype
hypoxia inducible factor
inflammation
airway
HIF1A
rhinitis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.756645/full

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