Progress in structural and functional study of the bacterial phenylacetic acid catabolic pathway, its role in pathogenicity and antibiotic resistance

Progress in structural and functional study of the bacterial phenylacetic acid catabolic pathway, its role in pathogenicity and antibiotic resistance

Phenylacetic acid (PAA) is a central intermediate metabolite involved in bacterial degradation of aromatic components. The bacterial PAA pathway mainly contains 12 enzymes and a transcriptional regulator, which are involved in biofilm formation and antimicrobial activity. They are present in approxi...

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Bibliographic Details
Main Authors: Min Jiao, Wenbo He, Zhenlin Ouyang, Qindong Shi, Yurong Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Microbiology
Subjects:
phenylacetic acid pathway
aromatic metabolites
enzyme structure
pathogenicity
antibiotic resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.964019/full

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