Identification of a conserved maxicircle and unique minicircles as part of the mitochondrial genome of Leishmania martiniquensis strain PCM3 in Thailand

Identification of a conserved maxicircle and unique minicircles as part of the mitochondrial genome of Leishmania martiniquensis strain PCM3 in Thailand

Abstract Background The mitochondrial DNA of trypanosomatids, including Leishmania, is known as kinetoplast DNAs (kDNAs). The kDNAs form networks of hundreds of DNA circles that are evidently interlocked and require complex RNA editing. Previous studies showed that kDNA played a role in drug resista...

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Bibliographic Details
Main Authors: Pornchai Anuntasomboon, Suradej Siripattanapipong, Sasimanas Unajak, Kiattawee Choowongkomon, Richard Burchmore, Saovanee Leelayoova, Mathirut Mungthin, Teerasak E-kobon
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Parasites & Vectors
Subjects:
Leishmania
Leishmania martiniquensis
Kinetoplast
Maxicircle
Minicircle
Online Access:https://doi.org/10.1186/s13071-022-05592-1

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