Identification of circadian clock modulators from existing drugs

Identification of circadian clock modulators from existing drugs

Abstract Chronic circadian disruption due to shift work or frequent travel across time zones leads to jet‐lag and an increased risk of diabetes, cardiovascular disease, and cancer. The development of new pharmaceuticals to treat circadian disorders, however, is costly and hugely time‐consuming. We t...

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Bibliographic Details
Main Authors: T Katherine Tamai, Yusuke Nakane, Wataru Ota, Akane Kobayashi, Masateru Ishiguro, Naoya Kadofusa, Keisuke Ikegami, Kazuhiro Yagita, Yasufumi Shigeyoshi, Masaki Sudo, Taeko Nishiwaki‐Ohkawa, Ayato Sato, Takashi Yoshimura
Format: Article
Language:English
Published: Springer Nature 2018-05-01
Series:EMBO Molecular Medicine
Subjects:
circadian rhythms
DHEA
drug repurposing
jet‐lag
tyrosine kinases
Online Access:https://doi.org/10.15252/emmm.201708724

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