Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature review

The autologous platelet concentrates (APC) comprise of platelet rich plasma (PRP) and platelet rich fibrin (PRF). These platelet concentrates provide a rich source of growth factors and have been used alone or in combination with bone grafts (BG) during open flap debridement (OFD) to treat various p...

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Main Authors: Shrushti Mahendra Sukalkar, Vineet Kini
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of International Clinical Dental Research Organization
Subjects:
Online Access:http://www.jicdro.org/article.asp?issn=2231-0754;year=2021;volume=13;issue=1;spage=10;epage=16;aulast=Sukalkar
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author Shrushti Mahendra Sukalkar
Vineet Kini
author_facet Shrushti Mahendra Sukalkar
Vineet Kini
author_sort Shrushti Mahendra Sukalkar
collection DOAJ
description The autologous platelet concentrates (APC) comprise of platelet rich plasma (PRP) and platelet rich fibrin (PRF). These platelet concentrates provide a rich source of growth factors and have been used alone or in combination with bone grafts (BG) during open flap debridement (OFD) to treat various periodontal osseous defects. This literature review was performed to assess the effect of adjunctive use of autologous platelet concentrates (APC) in the surgical management of periodontal osseous defects. Literature search was performed through the databases of national library of medicine and EBSCO host using PubMed and Google scholar search engines and manual searches in which 36 randomized clinical trials (RCT) meeting inclusion criteria that evaluated the healing outcomes of Probing depth (PD) reduction, gain in clinical attachment level (CAL) , radiographic bone fill and defect fill in intervention of OFD+APC / OFD+BG +APC as compared to OFD/ OFD+BG in the treatment of periodontal osseous defects published between 2001 to 2019 were assessed. Upon assessment of literature the adjunctive use of APCs appears to have an additive effect to open flap debridement alone or along with bone grafts in surgical management of periodontal osseous defects.
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spelling doaj.art-c7bddfa8cb87441ba28346fad5fc5b792022-12-21T18:33:17ZengWolters Kluwer Medknow PublicationsJournal of International Clinical Dental Research Organization2231-07542021-01-01131101610.4103/jicdro.jicdro_38_20Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature reviewShrushti Mahendra SukalkarVineet KiniThe autologous platelet concentrates (APC) comprise of platelet rich plasma (PRP) and platelet rich fibrin (PRF). These platelet concentrates provide a rich source of growth factors and have been used alone or in combination with bone grafts (BG) during open flap debridement (OFD) to treat various periodontal osseous defects. This literature review was performed to assess the effect of adjunctive use of autologous platelet concentrates (APC) in the surgical management of periodontal osseous defects. Literature search was performed through the databases of national library of medicine and EBSCO host using PubMed and Google scholar search engines and manual searches in which 36 randomized clinical trials (RCT) meeting inclusion criteria that evaluated the healing outcomes of Probing depth (PD) reduction, gain in clinical attachment level (CAL) , radiographic bone fill and defect fill in intervention of OFD+APC / OFD+BG +APC as compared to OFD/ OFD+BG in the treatment of periodontal osseous defects published between 2001 to 2019 were assessed. Upon assessment of literature the adjunctive use of APCs appears to have an additive effect to open flap debridement alone or along with bone grafts in surgical management of periodontal osseous defects.http://www.jicdro.org/article.asp?issn=2231-0754;year=2021;volume=13;issue=1;spage=10;epage=16;aulast=Sukalkarautologous platelet concentratesfurcation defectsinfrabony defectsintrabony defectsplatelet-rich fibrinplatelet-rich plasma
spellingShingle Shrushti Mahendra Sukalkar
Vineet Kini
Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature review
Journal of International Clinical Dental Research Organization
autologous platelet concentrates
furcation defects
infrabony defects
intrabony defects
platelet-rich fibrin
platelet-rich plasma
title Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature review
title_full Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature review
title_fullStr Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature review
title_full_unstemmed Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature review
title_short Adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects: A literature review
title_sort adjunctive use of autologous platelet concentrates in surgical management of periodontal osseous defects a literature review
topic autologous platelet concentrates
furcation defects
infrabony defects
intrabony defects
platelet-rich fibrin
platelet-rich plasma
url http://www.jicdro.org/article.asp?issn=2231-0754;year=2021;volume=13;issue=1;spage=10;epage=16;aulast=Sukalkar
work_keys_str_mv AT shrushtimahendrasukalkar adjunctiveuseofautologousplateletconcentratesinsurgicalmanagementofperiodontalosseousdefectsaliteraturereview
AT vineetkini adjunctiveuseofautologousplateletconcentratesinsurgicalmanagementofperiodontalosseousdefectsaliteraturereview