Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity

Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity

Cancer is a multifactorial disease that may be tackled by targeting different signaling pathways. Heme oxygenase-1 (HO-1) and sigma receptors (σRs) are both overexpressed in different human cancers, including prostate and brain, contributing to the cancer spreading. In the present study, we investig...

Повний опис

Бібліографічні деталі
Автори: Giuseppe Romeo, Valeria Ciaffaglione, Emanuele Amata, Maria Dichiara, Loredana Calabrese, Luca Vanella, Valeria Sorrenti, Salvo Grosso, Agata Grazia D’Amico, Velia D’Agata, Sebastiano Intagliata, Loredana Salerno
Формат: Стаття
Мова:English
Опубліковано: MDPI AG 2021-06-01
Серія:Molecules
Предмети:
heme oxygenase
HO-1 inhibitors
sigma receptors
σR ligands
DU145
anticancer activity
Онлайн доступ:https://www.mdpi.com/1420-3049/26/13/3860

Інтернет

https://www.mdpi.com/1420-3049/26/13/3860

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