Effect of UDP-Glucuronosyltransferase (UGT) 1A Polymorphism (rs8330 and rs10929303) on Glucuronidation Status of Acetaminophen
Interindividual variability in polymorphic uridine diphosphate-glucuronosyltransferase 1A1 (UGT1A1) ascribed to genetic diversity is associated with relative glucuronidation level among individuals. The present research was aimed to study the effect of 2 important single nucleotide polymorphisms (SN...
Main Authors: | Huma Mehboob, Imtiaz Mahmood Tahir, Tahira Iqbal, Sadaf Saleem, Sofia Perveen, Aboubakker Farooqi |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-09-01
|
Series: | Dose-Response |
Online Access: | https://doi.org/10.1177/1559325817723731 |
Similar Items
-
Identification and interspecies characterization of UDP-glucuronosyltransferase isoforms catalyzing acacetin glucuronidation using recombinant UGT enzymes and microsomes
by: Kangle Shi, et al.
Published: (2019-04-01) -
Identification of Bromophenols' glucuronidation and its induction on UDP- glucuronosyltransferases isoforms
by: Haoqian Zhang, et al.
Published: (2024-05-01) -
Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis
by: Wanying Zeng, et al.
Published: (2022-11-01) -
Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences
by: Juan Chen, et al.
Published: (2023-01-01) -
Inhibitory Effect of Sauchinone on UDP-Glucuronosyltransferase (UGT) 2B7 Activity
by: Byoung Hoon You, et al.
Published: (2018-02-01)