Overexpression of HHLA2 in human clear cell renal cell carcinoma is significantly associated with poor survival of the patients

Overexpression of HHLA2 in human clear cell renal cell carcinoma is significantly associated with poor survival of the patients

Abstract Background It is well known that human clear cell renal cell carcinoma (ccRCC) is a highly immunogenic and chemo-resistant tumor. Recently, emerging data suggest that the immune checkpoint blockade therapy is an important breakthrough in the treatment against ccRCC. HHLA2, a recently report...

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Bibliographic Details
Main Authors: Lujun Chen, Dawei Zhu, Jun Feng, You Zhou, Qi Wang, Huijing Feng, Junping Zhang, Jingting Jiang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Cancer Cell International
Subjects:
HHLA2
Clear cell renal cell carcinoma
Prognosis
Epithelial-to-mesenchymal transition
Online Access:http://link.springer.com/article/10.1186/s12935-019-0813-2

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