Enriched Alternative Splicing in Islets of Diabetes-Susceptible Mice

Enriched Alternative Splicing in Islets of Diabetes-Susceptible Mice

Dysfunctional islets of Langerhans are a hallmark of type 2 diabetes (T2D). We hypothesize that differences in islet gene expression alternative splicing which can contribute to altered protein function also participate in islet dysfunction. RNA sequencing (RNAseq) data from islets of obese diabetes...

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Bibliographic Details
Main Authors: Ilka Wilhelmi, Alexander Neumann, Markus Jähnert, Meriem Ouni, Annette Schürmann
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
alternative splicing
epigenetic
MicroRNA
RNAseq
diabetes
β-cell failure
Online Access:https://www.mdpi.com/1422-0067/22/16/8597

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