Semi-Automated Assessment of Human Islet Viability Predicts Transplantation Outcomes in a Diabetic Mouse Model
In clinical and experimental human pancreatic islet transplantations, establishing pretransplant assessments that accurately predict transplantation outcomes is crucial. Conventional in vitro viability assessment that relies on manual counting of viable islets is a routine pretransplant assessment....
Main Authors: | Mayra Salgado, Nelson Gonzalez, Leonard Medrano, Jeffrey Rawson, Keiko Omori, Meirigeng Qi, Ismail Al-Abdullah, Fouad Kandeel, Yoko Mullen, Hirotake Komatsu |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2020-05-01
|
Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/0963689720919444 |
Similar Items
-
Determination of Islet Viability Using a Zinc-Specific Fluorescent Dye and a Semiautomated Assessment Method
by: Hirotake Komatsu, et al.
Published: (2016-10-01) -
Microwell culture platform maintains viability and mass of human pancreatic islets
by: Hiroyuki Kato, et al.
Published: (2022-11-01) -
A Multiparametric Assessment of Human Islets Predicts Transplant Outcomes in Diabetic Mice
by: Hirotake Komatsu MD, PhD, et al.
Published: (2021-10-01) -
Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival.
by: Hirotake Komatsu, et al.
Published: (2017-01-01) -
Human Pancreatic Islets Isolated from Donors with Elevated HbA1c Levels: Islet Yield and Graft Efficacy
by: Meirigeng Qi, et al.
Published: (2015-09-01)