Study of the Interactions of Bovine Serum Albumin with the New Anti-Inflammatory Agent 4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N′-[(4-ethoxy-phenyl)methylidene]benzohydrazide Using a Multi-Spectroscopic Approach and Molecular Docking

Study of the Interactions of Bovine Serum Albumin with the New Anti-Inflammatory Agent 4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-N′-[(4-ethoxy-phenyl)methylidene]benzohydrazide Using a Multi-Spectroscopic Approach and Molecular Docking

The lipophilic derivative of thalidomide (4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N′-[(4-ethoxyphenyl)methylidene]benzohydrazide, 6P) was synthesized to enhance its characteristics and efficacy. Earlier studies have proved the immunomodulatory and anti-inflammatory effects of 6P. In this study th...

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Bibliographic Details
Main Authors: Tanveer A. Wani, Ahmed H. Bakheit, Abdul-Rahman A. Al-Majed, Mashooq A. Bhat, Seema Zargar
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Molecules
Subjects:
HSA
BSA
serum albumin
thalidomide
lipophilic thalidomide derivative
fluorescence
quenching
6P
Online Access:https://www.mdpi.com/1420-3049/22/8/1258

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