A randomized, double-blind, and placebo-controlled study with tranexamic acid of bleeding and fibrinolytic activity after primary coronary artery bypass grafting

A randomized, double-blind, and placebo-controlled study with tranexamic acid of bleeding and fibrinolytic activity after primary coronary artery bypass grafting

Cardiopulmonary bypass is frequently associated with excessive blood loss. Platelet dysfunction is the main cause of non-surgical bleeding after open-heart surgery. We randomized 65 patients in a double-blind fashion to receive tranexamic acid or placebo in order to determine whether antifibrinolyti...

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Bibliographic Details
Main Authors: A.T.L. Santos, R.A.K. Kalil, C. Bauemann, J.B. Pereira, I.A. Nesralla
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Tranexamic acid
Coronary artery bypass
Postoperative bleeding
Clinical trial
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000100007

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