Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity
Plants are rich in phytoconstituent biomolecules that served as a good source of medicine. More recently, they have been employed in synthesizing metal/metal oxide nanoparticles (NPs) due to their capping and reducing properties. This green synthesis approach is environmentally friendly and allows t...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/11/4/564 |
| _version_ | 1797538014018142208 |
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| author | Devanthiran Letchumanan Sophia P. M. Sok Suriani Ibrahim Noor Hasima Nagoor Norhafiza Mohd Arshad |
| author_facet | Devanthiran Letchumanan Sophia P. M. Sok Suriani Ibrahim Noor Hasima Nagoor Norhafiza Mohd Arshad |
| author_sort | Devanthiran Letchumanan |
| collection | DOAJ |
| description | Plants are rich in phytoconstituent biomolecules that served as a good source of medicine. More recently, they have been employed in synthesizing metal/metal oxide nanoparticles (NPs) due to their capping and reducing properties. This green synthesis approach is environmentally friendly and allows the production of the desired NPs in different sizes and shapes by manipulating parameters during the synthesis process. The most commonly used metals and oxides are gold (Au), silver (Ag), and copper (Cu). Among these, Cu is a relatively low-cost metal that is more cost-effective than Au and Ag. In this review, we present an overview and current update of plant-mediated Cu/copper oxide (CuO) NPs, including their synthesis, medicinal applications, and mechanisms. Furthermore, the toxic effects of these NPs and their efficacy compared to commercial NPs are reviewed. This review provides an insight into the potential of developing plant-based Cu/CuO NPs as a therapeutic agent for various diseases in the future. |
| first_indexed | 2024-03-10T12:24:25Z |
| format | Article |
| id | doaj.art-c7d4d797fb1241eaa68b8d6123edb72f |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T12:24:25Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-c7d4d797fb1241eaa68b8d6123edb72f2023-11-21T15:12:11ZengMDPI AGBiomolecules2218-273X2021-04-0111456410.3390/biom11040564Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and ToxicityDevanthiran Letchumanan0Sophia P. M. Sok1Suriani Ibrahim2Noor Hasima Nagoor3Norhafiza Mohd Arshad4Centre for Research in Biotechnology for Agriculture, University of Malaya, Kuala Lumpur 50603, MalaysiaCentre for Research in Biotechnology for Agriculture, University of Malaya, Kuala Lumpur 50603, MalaysiaDepartment of Mechanical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur 50603, MalaysiaCentre for Research in Biotechnology for Agriculture, University of Malaya, Kuala Lumpur 50603, MalaysiaCentre for Research in Biotechnology for Agriculture, University of Malaya, Kuala Lumpur 50603, MalaysiaPlants are rich in phytoconstituent biomolecules that served as a good source of medicine. More recently, they have been employed in synthesizing metal/metal oxide nanoparticles (NPs) due to their capping and reducing properties. This green synthesis approach is environmentally friendly and allows the production of the desired NPs in different sizes and shapes by manipulating parameters during the synthesis process. The most commonly used metals and oxides are gold (Au), silver (Ag), and copper (Cu). Among these, Cu is a relatively low-cost metal that is more cost-effective than Au and Ag. In this review, we present an overview and current update of plant-mediated Cu/copper oxide (CuO) NPs, including their synthesis, medicinal applications, and mechanisms. Furthermore, the toxic effects of these NPs and their efficacy compared to commercial NPs are reviewed. This review provides an insight into the potential of developing plant-based Cu/CuO NPs as a therapeutic agent for various diseases in the future.https://www.mdpi.com/2218-273X/11/4/564copper/copper oxidegreen synthesisnanoparticlesbiomedicinemechanismtoxicity |
| spellingShingle | Devanthiran Letchumanan Sophia P. M. Sok Suriani Ibrahim Noor Hasima Nagoor Norhafiza Mohd Arshad Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity Biomolecules copper/copper oxide green synthesis nanoparticles biomedicine mechanism toxicity |
| title | Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity |
| title_full | Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity |
| title_fullStr | Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity |
| title_full_unstemmed | Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity |
| title_short | Plant-Based Biosynthesis of Copper/Copper Oxide Nanoparticles: An Update on Their Applications in Biomedicine, Mechanisms, and Toxicity |
| title_sort | plant based biosynthesis of copper copper oxide nanoparticles an update on their applications in biomedicine mechanisms and toxicity |
| topic | copper/copper oxide green synthesis nanoparticles biomedicine mechanism toxicity |
| url | https://www.mdpi.com/2218-273X/11/4/564 |
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