Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infection
There are increasing concerns regarding the role global climate change will have on many vector-borne diseases. Both mathematical models and laboratory experiments suggest that schistosomiasis risk may change as a result of the effects of increasing temperatures on the planorbid snails that host sch...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2020-04-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/9059.pdf |
| _version_ | 1797419390412521472 |
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| author | Euan R.O. Allan Stephanie Bollmann Ekaterina Peremyslova Michael Blouin |
| author_facet | Euan R.O. Allan Stephanie Bollmann Ekaterina Peremyslova Michael Blouin |
| author_sort | Euan R.O. Allan |
| collection | DOAJ |
| description | There are increasing concerns regarding the role global climate change will have on many vector-borne diseases. Both mathematical models and laboratory experiments suggest that schistosomiasis risk may change as a result of the effects of increasing temperatures on the planorbid snails that host schistosomes. Heat pulse/heat shock of the BS90 strain of Biomphalaria glabrata was shown to increase the rate of infection by Schistosoma mansoni, but the result was not replicable in a follow up experiment by a different lab. We characterised the susceptibility and cercarial shedding of Guadeloupean B. glabrata after infection with S. mansoni under two temperature regimes: multigenerational exposure to small increases in temperature, and extreme heat pulse events. Neither long-term, multigenerational rearing at elevated temperatures, nor transient heat pulse modified the susceptibility of Guadeloupean B. glabrata to infection (prevalence) or shedding of schistosome cercaria (intensity of infection). These findings suggest that heat pulse-induced susceptibility in snail hosts may be dependent on the strain of the snail and/or schistosome, or on some as-yet unidentified environmental co-factor. |
| first_indexed | 2024-03-09T06:47:35Z |
| format | Article |
| id | doaj.art-c7ed556d1ca84da8a497bf96da861eca |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T06:47:35Z |
| publishDate | 2020-04-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
| series | PeerJ |
| spelling | doaj.art-c7ed556d1ca84da8a497bf96da861eca2023-12-03T10:34:26ZengPeerJ Inc.PeerJ2167-83592020-04-018e905910.7717/peerj.9059Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infectionEuan R.O. Allan0Stephanie Bollmann1Ekaterina Peremyslova2Michael Blouin3School of Veterinary Medicine, Pathobiology, St. George’s University, St. George’s, GrenadaIntegrative Biology, Oregon State University, Corvallis, OR, United States of AmericaIntegrative Biology, Oregon State University, Corvallis, OR, United States of AmericaIntegrative Biology, Oregon State University, Corvallis, OR, United States of AmericaThere are increasing concerns regarding the role global climate change will have on many vector-borne diseases. Both mathematical models and laboratory experiments suggest that schistosomiasis risk may change as a result of the effects of increasing temperatures on the planorbid snails that host schistosomes. Heat pulse/heat shock of the BS90 strain of Biomphalaria glabrata was shown to increase the rate of infection by Schistosoma mansoni, but the result was not replicable in a follow up experiment by a different lab. We characterised the susceptibility and cercarial shedding of Guadeloupean B. glabrata after infection with S. mansoni under two temperature regimes: multigenerational exposure to small increases in temperature, and extreme heat pulse events. Neither long-term, multigenerational rearing at elevated temperatures, nor transient heat pulse modified the susceptibility of Guadeloupean B. glabrata to infection (prevalence) or shedding of schistosome cercaria (intensity of infection). These findings suggest that heat pulse-induced susceptibility in snail hosts may be dependent on the strain of the snail and/or schistosome, or on some as-yet unidentified environmental co-factor.https://peerj.com/articles/9059.pdfBiomphalaria glabrataClimate changeHeat shockSchistosomiasisHeat pulse |
| spellingShingle | Euan R.O. Allan Stephanie Bollmann Ekaterina Peremyslova Michael Blouin Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infection PeerJ Biomphalaria glabrata Climate change Heat shock Schistosomiasis Heat pulse |
| title | Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infection |
| title_full | Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infection |
| title_fullStr | Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infection |
| title_full_unstemmed | Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infection |
| title_short | Neither heat pulse, nor multigenerational exposure to a modest increase in water temperature, alters the susceptibility of Guadeloupean Biomphalaria glabrata to Schistosoma mansoni infection |
| title_sort | neither heat pulse nor multigenerational exposure to a modest increase in water temperature alters the susceptibility of guadeloupean biomphalaria glabrata to schistosoma mansoni infection |
| topic | Biomphalaria glabrata Climate change Heat shock Schistosomiasis Heat pulse |
| url | https://peerj.com/articles/9059.pdf |
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