Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis

Choriocarcinoma presents usually as persistent trophoblastic disease, with prognosis worsening with duration from antecedent pregnancy. We present a unique case of a woman with choriocarcinoma who presented in the third trimester of pregnancy with eclampsia. She was managed with magnesium sulphate...

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Main Authors: Sujata Siwatch, Vanita Suri, Pooja Sikka, Neelam Aggarwal, Seema Chopra
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-11-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/8769/19344_CE(RA1)_F(T)_PF1(ASAK)_PFA(NC_AK)_PF2(PAG).pdf
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author Sujata Siwatch
Vanita Suri
Pooja Sikka
Neelam Aggarwal
Seema Chopra
author_facet Sujata Siwatch
Vanita Suri
Pooja Sikka
Neelam Aggarwal
Seema Chopra
author_sort Sujata Siwatch
collection DOAJ
description Choriocarcinoma presents usually as persistent trophoblastic disease, with prognosis worsening with duration from antecedent pregnancy. We present a unique case of a woman with choriocarcinoma who presented in the third trimester of pregnancy with eclampsia. She was managed with magnesium sulphate and underwent a caesarean section. However, she developed seizures in the post-partum period that were further investigated and attributed to intracranial metastatic lesions of Gestational Trophoblastic Neoplasia (GTN). We discussed the diagnostic challenge in this rare case of GTN and the grave potential it can have in such a presentation, as in our patient.
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spelling doaj.art-c7ee5c6379564d99a1d6cc94ae2b04652022-12-22T00:35:08ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-11-011011QD01QD0310.7860/JCDR/2016/19344.8769Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial MetastasisSujata Siwatch0Vanita Suri1Pooja Sikka2Neelam Aggarwal3Seema Chopra4Assistant Professor, Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India.Professor, Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India.Associate Professor, Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India.Additional Professor, Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India.Associate Professor, Department of Obstetrics and Gynecology, PGIMER, Chandigarh, India.Choriocarcinoma presents usually as persistent trophoblastic disease, with prognosis worsening with duration from antecedent pregnancy. We present a unique case of a woman with choriocarcinoma who presented in the third trimester of pregnancy with eclampsia. She was managed with magnesium sulphate and underwent a caesarean section. However, she developed seizures in the post-partum period that were further investigated and attributed to intracranial metastatic lesions of Gestational Trophoblastic Neoplasia (GTN). We discussed the diagnostic challenge in this rare case of GTN and the grave potential it can have in such a presentation, as in our patient.https://jcdr.net/articles/PDF/8769/19344_CE(RA1)_F(T)_PF1(ASAK)_PFA(NC_AK)_PF2(PAG).pdfeclampsiagestational trophoblastic diseasemagnesium sulphate
spellingShingle Sujata Siwatch
Vanita Suri
Pooja Sikka
Neelam Aggarwal
Seema Chopra
Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis
Journal of Clinical and Diagnostic Research
eclampsia
gestational trophoblastic disease
magnesium sulphate
title Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis
title_full Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis
title_fullStr Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis
title_full_unstemmed Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis
title_short Choriocarcinoma in Ongoing Pregnancy Presenting with Intracranial Metastasis
title_sort choriocarcinoma in ongoing pregnancy presenting with intracranial metastasis
topic eclampsia
gestational trophoblastic disease
magnesium sulphate
url https://jcdr.net/articles/PDF/8769/19344_CE(RA1)_F(T)_PF1(ASAK)_PFA(NC_AK)_PF2(PAG).pdf
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AT vanitasuri choriocarcinomainongoingpregnancypresentingwithintracranialmetastasis
AT poojasikka choriocarcinomainongoingpregnancypresentingwithintracranialmetastasis
AT neelamaggarwal choriocarcinomainongoingpregnancypresentingwithintracranialmetastasis
AT seemachopra choriocarcinomainongoingpregnancypresentingwithintracranialmetastasis