The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children
The article presents modern information on the clinical application, effectiveness and safety of the first-generation H1-antihistamine — dimetindene maleate. A brief description of the drug is given, the main indicators of its pharmacokinetics and pharmacodynamics are described. The attention is fo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Zaslavsky O.Yu.
2018-05-01
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| Series: | Zdorovʹe Rebenka |
| Subjects: | |
| Online Access: | http://childshealth.zaslavsky.com.ua/article/view/137026 |
| _version_ | 1818322255960080384 |
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| author | A.E. Abaturov E.L. Krivusha E.A. Agafonova N.M. Tokarevа V.L. Babich |
| author_facet | A.E. Abaturov E.L. Krivusha E.A. Agafonova N.M. Tokarevа V.L. Babich |
| author_sort | A.E. Abaturov |
| collection | DOAJ |
| description | The article presents modern information on the clinical application, effectiveness and safety of the first-generation H1-antihistamine — dimetindene maleate. A brief description of the drug is given, the main indicators of its pharmacokinetics and pharmacodynamics are described. The attention is focused on the main pharmacological mechanisms of the clinical effects of the drug. An analysis of the results of clinical studies using dimetindene maleate in allergic and infectious diseases of the skin in children has been carried out. A brief description is given of the drug Phenokit appeared on the pharmaceutical market of Ukraine, the main indications for its administration are substantiated. |
| first_indexed | 2024-12-13T10:53:54Z |
| format | Article |
| id | doaj.art-c7ef865bee2a4f9986a22fb0182b9dc8 |
| institution | Directory Open Access Journal |
| issn | 2224-0551 2307-1168 |
| language | English |
| last_indexed | 2024-12-13T10:53:54Z |
| publishDate | 2018-05-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Zdorovʹe Rebenka |
| spelling | doaj.art-c7ef865bee2a4f9986a22fb0182b9dc82022-12-21T23:49:43ZengZaslavsky O.Yu.Zdorovʹe Rebenka2224-05512307-11682018-05-0113439440010.22141/2224-0551.13.4.2018.137026137026The effectiveness of first-generation antihistamines in the treatment of allergic diseases in childrenA.E. Abaturov0E.L. Krivusha1E.A. Agafonova2N.M. Tokarevа3V.L. Babich4State Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, UkraineState Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, UkraineState Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, UkraineState Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, UkraineState Institution “Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine”, Dnipro, UkraineThe article presents modern information on the clinical application, effectiveness and safety of the first-generation H1-antihistamine — dimetindene maleate. A brief description of the drug is given, the main indicators of its pharmacokinetics and pharmacodynamics are described. The attention is focused on the main pharmacological mechanisms of the clinical effects of the drug. An analysis of the results of clinical studies using dimetindene maleate in allergic and infectious diseases of the skin in children has been carried out. A brief description is given of the drug Phenokit appeared on the pharmaceutical market of Ukraine, the main indications for its administration are substantiated.http://childshealth.zaslavsky.com.ua/article/view/137026childrenallergic diseasesatopic dermatitisH1-antihistaminestreatment |
| spellingShingle | A.E. Abaturov E.L. Krivusha E.A. Agafonova N.M. Tokarevа V.L. Babich The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children Zdorovʹe Rebenka children allergic diseases atopic dermatitis H1-antihistamines treatment |
| title | The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children |
| title_full | The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children |
| title_fullStr | The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children |
| title_full_unstemmed | The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children |
| title_short | The effectiveness of first-generation antihistamines in the treatment of allergic diseases in children |
| title_sort | effectiveness of first generation antihistamines in the treatment of allergic diseases in children |
| topic | children allergic diseases atopic dermatitis H1-antihistamines treatment |
| url | http://childshealth.zaslavsky.com.ua/article/view/137026 |
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