Caging the Beast: TRIM5α Binding to the HIV-1 Core

Caging the Beast: TRIM5α Binding to the HIV-1 Core

The potent HIV-1 inhibitor TRIM5α blocks HIV-1 infection by accelerating the uncoating of HIV-1. TRIM5α is known to form higher-order self-association complexes that contribute to the avidity of TRIM5α for the HIV-1 capsid, and are essential to inhibit infection; these higher-order self-association...

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Bibliographic Details
Main Author:	Felipe Diaz-Griffero
Format:	Article
Language:	English
Published:	MDPI AG 2011-04-01
Series:	Viruses
Subjects:	HIV-1 TRIM5α capsid binding core
Online Access:	http://www.mdpi.com/1999-4915/3/5/423/

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