Development of a clinical and translational research curriculum for undergraduate students

Abstract Introduction: Research participation during undergraduate years has a powerful influence on career selection and attitudes toward scientific research. Most undergraduate research programs in academic health centers are oriented toward basic research or address a particular disease focus o...

Full description

Bibliographic Details
Main Authors: Laura James, Tara Venable, Andres Caro, Jeffrey H. Moran, Claire Nesmith, Matthew A. Gannon, Lawrence E. Cornett
Format: Article
Language:English
Published: Cambridge University Press 2023-01-01
Series:Journal of Clinical and Translational Science
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2059866123005320/type/journal_article
_version_ 1797817382054395904
author Laura James
Tara Venable
Andres Caro
Jeffrey H. Moran
Claire Nesmith
Matthew A. Gannon
Lawrence E. Cornett
author_facet Laura James
Tara Venable
Andres Caro
Jeffrey H. Moran
Claire Nesmith
Matthew A. Gannon
Lawrence E. Cornett
author_sort Laura James
collection DOAJ
description Abstract Introduction: Research participation during undergraduate years has a powerful influence on career selection and attitudes toward scientific research. Most undergraduate research programs in academic health centers are oriented toward basic research or address a particular disease focus or research discipline. Undergraduate research programs that expose students to clinical and translational research may alter student perceptions about research and influence career selection. Methods: We developed an undergraduate summer research curriculum, anchored upon a clinical and translational research study developed to address a common unmet needs in neonatal nurseries (e.g., assessment of neonatal opioid withdrawal syndrome). Program topics reflected the cross-disciplinary expertise that contributed to the development of this “bedside to bench” study, including opioid addiction, vulnerable populations, research ethics, statistics, data collection and management, assay development, analytical laboratory analysis, and pharmacokinetics. The curriculum was delivered through three offerings over 12 months, using Zoom video-conferencing due to restrictions imposed by the COVID-19 pandemic. Results: Nine students participated in the program. Two-thirds reported the course enhanced their understanding of clinical and translational research. Over three-quarters reported the curriculum topics were very good or excellent. In open-ended questions, students reported that the cross-disciplinary nature of the curriculum was the strongest aspect of the program. Conclusion: The curriculum could be readily adapted by other Clinical and Translational Science Award programs seeking to provide clinical and translational research-oriented programs to undergraduate students. Application of cross-disciplinary research approaches to a specific clinical and translational research question provides students with relevant examples of translational research and translational science.
first_indexed 2024-03-13T08:52:37Z
format Article
id doaj.art-c7f2248c603a48e0a689c4e842b6262c
institution Directory Open Access Journal
issn 2059-8661
language English
last_indexed 2024-03-13T08:52:37Z
publishDate 2023-01-01
publisher Cambridge University Press
record_format Article
series Journal of Clinical and Translational Science
spelling doaj.art-c7f2248c603a48e0a689c4e842b6262c2023-05-29T09:05:39ZengCambridge University PressJournal of Clinical and Translational Science2059-86612023-01-01710.1017/cts.2023.532Development of a clinical and translational research curriculum for undergraduate studentsLaura James0Tara Venable1Andres Caro2Jeffrey H. Moran3Claire Nesmith4Matthew A. Gannon5Lawrence E. Cornett6The Departments of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USAThe Departments of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USADepartment of Chemistry, Hendrix College, Conway, AR, USADepartment of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR, USAThe Departments of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USACommunity Health and Research, University of Arkansas for Medical Sciences, Little Rock, AR, USADepartment of Physiology and Cell Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA Abstract Introduction: Research participation during undergraduate years has a powerful influence on career selection and attitudes toward scientific research. Most undergraduate research programs in academic health centers are oriented toward basic research or address a particular disease focus or research discipline. Undergraduate research programs that expose students to clinical and translational research may alter student perceptions about research and influence career selection. Methods: We developed an undergraduate summer research curriculum, anchored upon a clinical and translational research study developed to address a common unmet needs in neonatal nurseries (e.g., assessment of neonatal opioid withdrawal syndrome). Program topics reflected the cross-disciplinary expertise that contributed to the development of this “bedside to bench” study, including opioid addiction, vulnerable populations, research ethics, statistics, data collection and management, assay development, analytical laboratory analysis, and pharmacokinetics. The curriculum was delivered through three offerings over 12 months, using Zoom video-conferencing due to restrictions imposed by the COVID-19 pandemic. Results: Nine students participated in the program. Two-thirds reported the course enhanced their understanding of clinical and translational research. Over three-quarters reported the curriculum topics were very good or excellent. In open-ended questions, students reported that the cross-disciplinary nature of the curriculum was the strongest aspect of the program. Conclusion: The curriculum could be readily adapted by other Clinical and Translational Science Award programs seeking to provide clinical and translational research-oriented programs to undergraduate students. Application of cross-disciplinary research approaches to a specific clinical and translational research question provides students with relevant examples of translational research and translational science. https://www.cambridge.org/core/product/identifier/S2059866123005320/type/journal_articleTeam scienceundergraduatetranslational researchcross-disciplinary researchcareer developmentbiomedical research
spellingShingle Laura James
Tara Venable
Andres Caro
Jeffrey H. Moran
Claire Nesmith
Matthew A. Gannon
Lawrence E. Cornett
Development of a clinical and translational research curriculum for undergraduate students
Journal of Clinical and Translational Science
Team science
undergraduate
translational research
cross-disciplinary research
career development
biomedical research
title Development of a clinical and translational research curriculum for undergraduate students
title_full Development of a clinical and translational research curriculum for undergraduate students
title_fullStr Development of a clinical and translational research curriculum for undergraduate students
title_full_unstemmed Development of a clinical and translational research curriculum for undergraduate students
title_short Development of a clinical and translational research curriculum for undergraduate students
title_sort development of a clinical and translational research curriculum for undergraduate students
topic Team science
undergraduate
translational research
cross-disciplinary research
career development
biomedical research
url https://www.cambridge.org/core/product/identifier/S2059866123005320/type/journal_article
work_keys_str_mv AT laurajames developmentofaclinicalandtranslationalresearchcurriculumforundergraduatestudents
AT taravenable developmentofaclinicalandtranslationalresearchcurriculumforundergraduatestudents
AT andrescaro developmentofaclinicalandtranslationalresearchcurriculumforundergraduatestudents
AT jeffreyhmoran developmentofaclinicalandtranslationalresearchcurriculumforundergraduatestudents
AT clairenesmith developmentofaclinicalandtranslationalresearchcurriculumforundergraduatestudents
AT matthewagannon developmentofaclinicalandtranslationalresearchcurriculumforundergraduatestudents
AT lawrenceecornett developmentofaclinicalandtranslationalresearchcurriculumforundergraduatestudents