Biodegradable magnesium implant enhances angiogenesis and alleviates medication-related osteonecrosis of the jaw in rats

Biodegradable magnesium implant enhances angiogenesis and alleviates medication-related osteonecrosis of the jaw in rats

Background: Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication associated with antiresorptive and antiangiogenic medications, of which impaired angiogenesis is a key pathological alteration. Since Magnesium (Mg)-based implants possess proangiogenic effects, we hypothesized...

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Bibliographic Details
Main Authors:	Wang-yong Zhu, Jiaxin Guo, Wei-fa Yang, Zhuo-ying Tao, Xinmiao Lan, Leilei Wang, Jiankun Xu, Ling Qin, Yu-xiong Su
Format:	Article
Language:	English
Published:	Elsevier 2022-03-01
Series:	Journal of Orthopaedic Translation
Subjects:	Angiogenesis Biodegradable implants Bisphosphonate Magnesium Medication-related osteonecrosis of the jaw
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X22000249

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