A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated Complications
Obesity has become a worldwide epidemic and its prevalence continues to increase at an alarming rate. It is considered a major risk factor for the development of several comorbidities, including type 2 diabetes, stroke, other cardiovascular diseases and even cancer. Conventional treatments for obesi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/12/18/3210 |
| _version_ | 1797577843511656448 |
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| author | Siti Hajar Adam Izuddin Fahmy Abu Datu Agasi Mohd Kamal Ami Febriza Mohd Izhar Ariff Mohd Kashim Mohd Helmy Mokhtar |
| author_facet | Siti Hajar Adam Izuddin Fahmy Abu Datu Agasi Mohd Kamal Ami Febriza Mohd Izhar Ariff Mohd Kashim Mohd Helmy Mokhtar |
| author_sort | Siti Hajar Adam |
| collection | DOAJ |
| description | Obesity has become a worldwide epidemic and its prevalence continues to increase at an alarming rate. It is considered a major risk factor for the development of several comorbidities, including type 2 diabetes, stroke, other cardiovascular diseases and even cancer. Conventional treatments for obesity, such as dietary interventions, exercise and pharmacotherapy, have proven to have limited effectiveness and are often associated with undesirable side effects. Therefore, there is a growing interest in exploring alternative therapeutic approaches. <i>Nigella sativa</i> (NS), a medicinal plant with multiple pharmacological properties, has gained attention due to its potential role in the treatment of obesity and its associated complications. The aim of this review is therefore to assess the effects of NS on obesity and its complications and to provide insights into the underlying mechanisms. From this review, NS appears to play a complementary or supportive role in the treatment of obesity and its complications. However, future studies are needed to verify the efficacy of NS in the treatment of obesity and its complications and to prove its safety so that it can be introduced in patients with obesity. |
| first_indexed | 2024-03-10T22:13:42Z |
| format | Article |
| id | doaj.art-c7fc05f1182d4107b6e2dcdb56d0b1b2 |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-10T22:13:42Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-c7fc05f1182d4107b6e2dcdb56d0b1b22023-11-19T12:31:38ZengMDPI AGPlants2223-77472023-09-011218321010.3390/plants12183210A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated ComplicationsSiti Hajar Adam0Izuddin Fahmy Abu1Datu Agasi Mohd Kamal2Ami Febriza3Mohd Izhar Ariff Mohd Kashim4Mohd Helmy Mokhtar5Preclinical Department, Faculty of Medicine & Defence Health, Universiti Pertahanan Nasional Malaysia, Kuala Lumpur 57000, MalaysiaInstitute of Medical Science Technology, Universiti Kuala Lumpur, Jalan Sultan Ismail, Kuala Lumpur 50250, MalaysiaDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu 88400, MalaysiaDepartment of Physiology, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Kota Makassar 90221, IndonesiaCentre of Shariah, Faculty of Islamic Studies, Universiti Kebangsaan Malaysia, Bangi 43600, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, MalaysiaObesity has become a worldwide epidemic and its prevalence continues to increase at an alarming rate. It is considered a major risk factor for the development of several comorbidities, including type 2 diabetes, stroke, other cardiovascular diseases and even cancer. Conventional treatments for obesity, such as dietary interventions, exercise and pharmacotherapy, have proven to have limited effectiveness and are often associated with undesirable side effects. Therefore, there is a growing interest in exploring alternative therapeutic approaches. <i>Nigella sativa</i> (NS), a medicinal plant with multiple pharmacological properties, has gained attention due to its potential role in the treatment of obesity and its associated complications. The aim of this review is therefore to assess the effects of NS on obesity and its complications and to provide insights into the underlying mechanisms. From this review, NS appears to play a complementary or supportive role in the treatment of obesity and its complications. However, future studies are needed to verify the efficacy of NS in the treatment of obesity and its complications and to prove its safety so that it can be introduced in patients with obesity.https://www.mdpi.com/2223-7747/12/18/3210<i>Nigella sativa</i>thymoquinoneantioxidantsanti-obesitybody weight |
| spellingShingle | Siti Hajar Adam Izuddin Fahmy Abu Datu Agasi Mohd Kamal Ami Febriza Mohd Izhar Ariff Mohd Kashim Mohd Helmy Mokhtar A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated Complications Plants <i>Nigella sativa</i> thymoquinone antioxidants anti-obesity body weight |
| title | A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated Complications |
| title_full | A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated Complications |
| title_fullStr | A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated Complications |
| title_full_unstemmed | A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated Complications |
| title_short | A Review of the Potential Health Benefits of <i>Nigella sativa</i> on Obesity and Its Associated Complications |
| title_sort | review of the potential health benefits of i nigella sativa i on obesity and its associated complications |
| topic | <i>Nigella sativa</i> thymoquinone antioxidants anti-obesity body weight |
| url | https://www.mdpi.com/2223-7747/12/18/3210 |
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