Pre-Eclampsia-Associated Reduction in Placental Growth Factor Impaired Beta Cell Proliferation Through PI3k Signalling

Pre-Eclampsia-Associated Reduction in Placental Growth Factor Impaired Beta Cell Proliferation Through PI3k Signalling

Background/Aim: Reduction in serum placental growth factor (PLGF) frequently co-occurs with preeclampsia (PE) and gestational diabetes mellitus (GDM). Recently, we reported that impairment in gestational beta-cell mass growth may result from PE-associated reduction in PLGF and lead to development of...

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Bibliographic Details
Main Authors: Jun Li, Huanchun Ying, Guiyang Cai, Quan Guo, Lizhu Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Preeclampsia
Placental growth factor
Beta cell proliferation
MS1, PI3k signaling
Gestational diabetes mellitus
Online Access:http://www.karger.com/Article/FullText/374051

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