Identification of <i>NSP3</i> (<i>SH2D3C</i>) as a Prognostic Biomarker of Tumor Progression and Immune Evasion for Lung Cancer and Evaluation of Organosulfur Compounds from <i>Allium sativum</i> L. as Therapeutic Candidates

Identification of <i>NSP3</i> (<i>SH2D3C</i>) as a Prognostic Biomarker of Tumor Progression and Immune Evasion for Lung Cancer and Evaluation of Organosulfur Compounds from <i>Allium sativum</i> L. as Therapeutic Candidates

The multi-domain non-structural protein 3 (<i>NSP3</i>) is an oncogenic molecule that has been concomitantly implicated in the progression of coronavirus infection. However, its oncological role in lung cancer and whether it plays a role in modulating the tumor immune microenvironment is...

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Bibliographic Details
Main Authors: Yuan-Chieh Yeh, Bashir Lawal, Michael Hsiao, Tse-Hung Huang, Chi-Ying F. Huang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biomedicines
Subjects:
<i>NSP3 (SH2D3C)</i>
NSCLC
tumor microenvironment
immune infiltrations
dysfunctional T-cell phenotypes
in silico study
Online Access:https://www.mdpi.com/2227-9059/9/11/1582

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