Characterization of Long Non-Coding RNAs in Systemic Sclerosis Monocytes: A Potential Role for PSMB8-AS1 in Altered Cytokine Secretion

Characterization of Long Non-Coding RNAs in Systemic Sclerosis Monocytes: A Potential Role for PSMB8-AS1 in Altered Cytokine Secretion

Systemic sclerosis (SSc) is a chronic autoimmune disease mainly affecting the connective tissue. In SSc patients, monocytes are increased in circulation, infiltrate affected tissues, and show a pro-inflammatory activation status, including the so-called interferon (IFN) signature. We previously demo...

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Bibliographic Details
Main Authors: Nila H. Servaas, Barbara Mariotti, Maarten van der Kroef, Catharina G. K. Wichers, Aridaman Pandit, Flavia Bazzoni, Timothy R. D. J. Radstake, Marzia Rossato
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
systemic sclerosis
monocytes
long non-coding RNA
autoimmune
co-expression network
Online Access:https://www.mdpi.com/1422-0067/22/9/4365

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