Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic Liquid
We developed a facile and greener approach for the preparation of silica-aerogel-based ionogels using choline dihydrogen phosphate ionic liquid by the sol–gel approach. A series of silica-based aerogels as ionogels were prepared by varying the ionic liquid concentrations: 0.1, 0.5, 1, 3, 5, and 10 w...
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MDPI AG
2020-12-01
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| author | Seeni Meera Kamal Mohamed Rajavelu Murali Sankar Manikantan Syamala Kiran Sellamuthu N. Jaisankar Barbara Milow Asit Baran Mandal |
| author_facet | Seeni Meera Kamal Mohamed Rajavelu Murali Sankar Manikantan Syamala Kiran Sellamuthu N. Jaisankar Barbara Milow Asit Baran Mandal |
| author_sort | Seeni Meera Kamal Mohamed |
| collection | DOAJ |
| description | We developed a facile and greener approach for the preparation of silica-aerogel-based ionogels using choline dihydrogen phosphate ionic liquid by the sol–gel approach. A series of silica-based aerogels as ionogels were prepared by varying the ionic liquid concentrations: 0.1, 0.5, 1, 3, 5, and 10 wt %. The as-prepared ionogels were characterized using several analytical techniques, namely, attenuated total reflectance (ATR)/FT-IR, TGA, XRD, and particle size analyses. The role of ionic liquid in the viscoelastic properties of the sol–gel transition was monitored using time-dependent rheological measurements. The addition of ionic liquid to the sol–gel system favored the formation of a more interconnected silica network structure. The formation of a silica network structure during sol–gel hydrolysis and condensation was confirmed from <sup>29</sup>Si solid-state CP/MAS NMR spectra. The effect of the ionic liquid on the morphological properties was investigated using SEM and TEM studies. The cell viabilities of the prepared gel samples were clearly evident from the cytotoxicity assay studies using Swiss and HaCaT cells. The main advantages of using biocompatible ionic liquids for the preparation of these aerogels as ionogels are that they may be used for encapsulating biological molecules and retain their conformational stability for a longer duration. |
| first_indexed | 2024-03-10T13:43:56Z |
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| id | doaj.art-c8086c5f36324f2e8ac18ed95ed47058 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T13:43:56Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
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| series | Applied Sciences |
| spelling | doaj.art-c8086c5f36324f2e8ac18ed95ed470582023-11-21T02:48:50ZengMDPI AGApplied Sciences2076-34172020-12-0111120610.3390/app11010206Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic LiquidSeeni Meera Kamal Mohamed0Rajavelu Murali Sankar1Manikantan Syamala Kiran2Sellamuthu N. Jaisankar3Barbara Milow4Asit Baran Mandal5Polymer Science & Technology Division, Council of Scientific & Industrial Research (CSIR)-Central Leather Research Institute (CLRI), Adyar, Chennai 600020, Tamil Nadu, IndiaPolymer Science & Technology Division, Council of Scientific & Industrial Research (CSIR)-Central Leather Research Institute (CLRI), Adyar, Chennai 600020, Tamil Nadu, IndiaBiological Materials Laboratory, Council of Scientific & Industrial Research (CSIR)-Central Leather Research Institute (CLRI), Adyar, Chennai 600020, Tamil Nadu, IndiaPolymer Science & Technology Division, Council of Scientific & Industrial Research (CSIR)-Central Leather Research Institute (CLRI), Adyar, Chennai 600020, Tamil Nadu, IndiaDepartment of Aerogels and Aerogel Composites, Institute of Materials Research, German Aerospace Center (DLR), Linder Hoehe, 51147 Cologne, GermanyPolymer Science & Technology Division, Council of Scientific & Industrial Research (CSIR)-Central Leather Research Institute (CLRI), Adyar, Chennai 600020, Tamil Nadu, IndiaWe developed a facile and greener approach for the preparation of silica-aerogel-based ionogels using choline dihydrogen phosphate ionic liquid by the sol–gel approach. A series of silica-based aerogels as ionogels were prepared by varying the ionic liquid concentrations: 0.1, 0.5, 1, 3, 5, and 10 wt %. The as-prepared ionogels were characterized using several analytical techniques, namely, attenuated total reflectance (ATR)/FT-IR, TGA, XRD, and particle size analyses. The role of ionic liquid in the viscoelastic properties of the sol–gel transition was monitored using time-dependent rheological measurements. The addition of ionic liquid to the sol–gel system favored the formation of a more interconnected silica network structure. The formation of a silica network structure during sol–gel hydrolysis and condensation was confirmed from <sup>29</sup>Si solid-state CP/MAS NMR spectra. The effect of the ionic liquid on the morphological properties was investigated using SEM and TEM studies. The cell viabilities of the prepared gel samples were clearly evident from the cytotoxicity assay studies using Swiss and HaCaT cells. The main advantages of using biocompatible ionic liquids for the preparation of these aerogels as ionogels are that they may be used for encapsulating biological molecules and retain their conformational stability for a longer duration.https://www.mdpi.com/2076-3417/11/1/206aerogelsionogelssilicaionic liquidcholine dihydrogen phosphate |
| spellingShingle | Seeni Meera Kamal Mohamed Rajavelu Murali Sankar Manikantan Syamala Kiran Sellamuthu N. Jaisankar Barbara Milow Asit Baran Mandal Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic Liquid Applied Sciences aerogels ionogels silica ionic liquid choline dihydrogen phosphate |
| title | Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic Liquid |
| title_full | Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic Liquid |
| title_fullStr | Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic Liquid |
| title_full_unstemmed | Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic Liquid |
| title_short | Facile Preparation of Biocompatible and Transparent Silica Aerogels as Ionogels Using Choline Dihydrogen Phosphate Ionic Liquid |
| title_sort | facile preparation of biocompatible and transparent silica aerogels as ionogels using choline dihydrogen phosphate ionic liquid |
| topic | aerogels ionogels silica ionic liquid choline dihydrogen phosphate |
| url | https://www.mdpi.com/2076-3417/11/1/206 |
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