Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protection
Brahmi (Bacopa monnieri (L.) Wettst.) is extensively used as a nutritional supplement in various commercial products as the plant contains abundant phytochemicals and has antioxidant properties. This study assessed the phytochemical contents, antioxidant properties, and DNA damage protection among s...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024005401 |
| _version_ | 1797328690164531200 |
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| author | Junya Nopparat Kawee Sujipuli Kumrop Ratanasut Monthana Weerawatanakorn Surisak Prasarnpun Bussagon Thongbai Walailak Laothaworn Phithak Inthima |
| author_facet | Junya Nopparat Kawee Sujipuli Kumrop Ratanasut Monthana Weerawatanakorn Surisak Prasarnpun Bussagon Thongbai Walailak Laothaworn Phithak Inthima |
| author_sort | Junya Nopparat |
| collection | DOAJ |
| description | Brahmi (Bacopa monnieri (L.) Wettst.) is extensively used as a nutritional supplement in various commercial products as the plant contains abundant phytochemicals and has antioxidant properties. This study assessed the phytochemical contents, antioxidant properties, and DNA damage protection among seven Brahmi products sold through Thai online markets. Results showed that the P6 sample exhibited 3.5–7.5 fold higher bacoside contents than values observed in the other six product samples. The P6 sample also demonstrated the highest TTC, TFC, and TPC compared to the other brands. For antioxidant activity, the samples (P1–P7) displayed high capacity to scavenge DPPH free radicals with slightly significant differences ranging from 78.37 ± 0.25 to 87.21 ± 0.05 at p-value ≤0.01. The P6 sample showed strong protection against H2O2-induced oxidation of DNA strand breakage, indicating highly potent phytochemical compounds with effective free radical scavenging activity, and the ability to prevent DNA damage. The P6 sample showed promise as a valuable ingredient for the development of functional food products. However, further in vivo animal and clinical studies are required to explore the neuroprotective enhancement effects of Brahmi extracts. |
| first_indexed | 2024-03-08T06:55:19Z |
| format | Article |
| id | doaj.art-c809760ccb8045b8b48f58e7b0ad5fcf |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T06:55:19Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-c809760ccb8045b8b48f58e7b0ad5fcf2024-02-03T06:37:43ZengElsevierHeliyon2405-84402024-01-01102e24509Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protectionJunya Nopparat0Kawee Sujipuli1Kumrop Ratanasut2Monthana Weerawatanakorn3Surisak Prasarnpun4Bussagon Thongbai5Walailak Laothaworn6Phithak Inthima7Office of the Dean, Faculty of Science and Health Technology, Navamindradhiraj University, 3, White Road, Vajira Hospital, Dusit, Bangkok, 10300, ThailandCenter of Agricultural Biotechnology, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, Thailand; Department of Agricultural Science, Faculty of Agriculture Natural Resources and Environment, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, ThailandCenter of Agricultural Biotechnology, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, Thailand; Department of Agricultural Science, Faculty of Agriculture Natural Resources and Environment, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, ThailandDepartment of Agro-Industry, Faculty of Agriculture, Natural Resources and Environment, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, ThailandSchool of Medical Sciences, University of Phayao, Phayao, 56000, ThailandDepartment of Food Technology and Nutrition, Faculty of Technology, Mahasarakham University, Mahasarakham, 44150, ThailandDepartment of Biology, Faculty of Science, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, ThailandCenter of Agricultural Biotechnology, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, Thailand; Department of Biology, Faculty of Science, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok, 65000, Thailand; Corresponding author. Department of Biology, Faculty of Science, Naresuan University, 99 Moo 9, Tha Pho, Phitsanulok 65000, Thailand.Brahmi (Bacopa monnieri (L.) Wettst.) is extensively used as a nutritional supplement in various commercial products as the plant contains abundant phytochemicals and has antioxidant properties. This study assessed the phytochemical contents, antioxidant properties, and DNA damage protection among seven Brahmi products sold through Thai online markets. Results showed that the P6 sample exhibited 3.5–7.5 fold higher bacoside contents than values observed in the other six product samples. The P6 sample also demonstrated the highest TTC, TFC, and TPC compared to the other brands. For antioxidant activity, the samples (P1–P7) displayed high capacity to scavenge DPPH free radicals with slightly significant differences ranging from 78.37 ± 0.25 to 87.21 ± 0.05 at p-value ≤0.01. The P6 sample showed strong protection against H2O2-induced oxidation of DNA strand breakage, indicating highly potent phytochemical compounds with effective free radical scavenging activity, and the ability to prevent DNA damage. The P6 sample showed promise as a valuable ingredient for the development of functional food products. However, further in vivo animal and clinical studies are required to explore the neuroprotective enhancement effects of Brahmi extracts.http://www.sciencedirect.com/science/article/pii/S2405844024005401Bacopa monnieriOxidative stressQuality assessmentDNA protective effectHealth supplements |
| spellingShingle | Junya Nopparat Kawee Sujipuli Kumrop Ratanasut Monthana Weerawatanakorn Surisak Prasarnpun Bussagon Thongbai Walailak Laothaworn Phithak Inthima Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protection Heliyon Bacopa monnieri Oxidative stress Quality assessment DNA protective effect Health supplements |
| title | Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protection |
| title_full | Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protection |
| title_fullStr | Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protection |
| title_full_unstemmed | Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protection |
| title_short | Exploring the excellence of commercial Brahmi products from Thai online markets: Unraveling phytochemical contents, antioxidant properties and DNA damage protection |
| title_sort | exploring the excellence of commercial brahmi products from thai online markets unraveling phytochemical contents antioxidant properties and dna damage protection |
| topic | Bacopa monnieri Oxidative stress Quality assessment DNA protective effect Health supplements |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024005401 |
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