Key oncogenic signaling pathways affecting tumor-infiltrating lymphocytes infiltration in hepatocellular carcinoma: basic principles and recent advances

Key oncogenic signaling pathways affecting tumor-infiltrating lymphocytes infiltration in hepatocellular carcinoma: basic principles and recent advances

The incidence of hepatocellular carcinoma (HCC) ranks first among primary liver cancers, and its mortality rate exhibits a consistent annual increase. The treatment of HCC has witnessed a significant surge in recent years, with the emergence of targeted immune therapy as an adjunct to early surgical...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Xiang Wang, Zijun Yuan, Zhengbo Li, Xinyu He, Yinping Zhang, Xingyue Wang, Jiahong Su, Xu Wu, Mingxing Li, Fukuan Du, Yu Chen, Shuai Deng, Yueshui Zhao, Jing Shen, Tao Yi, Zhangang Xiao
Định dạng:	Bài viết
Ngôn ngữ:	English
Được phát hành:	Frontiers Media S.A. 2024-02-01
Loạt:	Frontiers in Immunology
Những chủ đề:	tumor-infiltrating lymphocytes (TILs) hepatocellular carcinoma (HCC) immunotherapy signaling pathway TILs preparation targeting neoantigens
Truy cập trực tuyến:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1354313/full

Những quyển sách tương tự

The investigation of oncolytic viruses in the field of cancer therapy
Bằng: Zijun Yuan, et al.
Được phát hành: (2024-07-01)

Emerging insights into the gut microbiota as a key regulator of immunity and response to immunotherapy in hepatocellular carcinoma
Bằng: Siqi Ren, et al.
Được phát hành: (2025-02-01)

Functional Peptides Encoded by Long Non-Coding RNAs in Gastrointestinal Cancer
Bằng: Yao Chen, et al.
Được phát hành: (2021-11-01)

Interaction of ncRNA and Epigenetic Modifications in Gastric Cancer: Focus on Histone Modification
Bằng: Qingfan Yang, et al.
Được phát hành: (2022-01-01)

Molecular profiling of core immune-escape genes highlights LCK as an immune-related prognostic biomarker in melanoma
Bằng: Fang Wang, et al.
Được phát hành: (2022-10-01)

Therapeutic prospects of ceRNAs in COVID-19
Bằng: Lin Liu, et al.
Được phát hành: (2022-09-01)

Synthesis of Oleanolic Acid-Dithiocarbamate Conjugates and Evaluation of Their Broad-Spectrum Antitumor Activities
Bằng: Liyao Tang, et al.
Được phát hành: (2023-02-01)

Vemurafenib inhibits immune escape biomarker BCL2A1 by targeting PI3K/AKT signaling pathway to suppress breast cancer
Bằng: Yalan Dai, et al.
Được phát hành: (2022-11-01)

Circular RNAs in the Regulation of Oxidative Stress
Bằng: Yao Zhang, et al.
Được phát hành: (2021-07-01)

Complex interaction and heterogeneity among cancer stem cells in head and neck squamous cell carcinoma revealed by single-cell sequencing
Bằng: Mintao Xiao, et al.
Được phát hành: (2022-11-01)

Fingerprint profiling for quality evaluation and the related biological activity analysis of polysaccharides from Liuweizhiji Gegen-Sangshen beverage
Bằng: Shulin Wei, et al.
Được phát hành: (2024-07-01)

Organoid, organ-on-a-chip and traditional Chinese medicine
Bằng: Jiayue Yang, et al.
Được phát hành: (2025-02-01)

Why do tumor-infiltrating lymphocytes have variable efficacy in the treatment of solid tumors?
Bằng: Biaoru Li
Được phát hành: (2022-10-01)

Comprehensive analysis of chemokines family and related regulatory ceRNA network in lung adenocarcinoma
Bằng: Yifan Hu, et al.
Được phát hành: (2022-11-01)

Targeting hypoxia-inducible factors for breast cancer therapy: A narrative review
Bằng: Shuang Luo, et al.
Được phát hành: (2022-12-01)

m5C RNA Methylation Primarily Affects the ErbB and PI3K–Akt Signaling Pathways in Gastrointestinal Cancer
Bằng: Shixin Xiang, et al.
Được phát hành: (2020-12-01)

Dysregulation of B7 family and its association with tumor microenvironment in uveal melanoma
Bằng: Yao Chen, et al.
Được phát hành: (2022-10-01)

Identification of Prognostic Genes in the Tumor Microenvironment of Hepatocellular Carcinoma
Bằng: Shixin Xiang, et al.
Được phát hành: (2021-04-01)

Comprehensive characterization of B7 family members in NSCLC and identification of its regulatory network
Bằng: Mintao Xiao, et al.
Được phát hành: (2023-03-01)

Engineered TCR-T Cell Immunotherapy in Anticancer Precision Medicine: Pros and Cons
Bằng: Qijie Zhao, et al.
Được phát hành: (2021-03-01)

HPV-associated cervicovaginal microbiome and host metabolome characteristics
Bằng: Yao Zhang, et al.
Được phát hành: (2024-03-01)

Identification of tumor stemness and immunity related prognostic factors and sensitive drugs in head and neck squamous cell carcinoma
Bằng: Zhihua Ye, et al.
Được phát hành: (2024-07-01)

Quercitrin, the primary active ingredient of Albizia julibrissin Durazz. flowers, alleviates methamphetamine-induced hepatotoxicity through a mitochondria-mediated apoptosis pathway
Bằng: Dan Wu, et al.
Được phát hành: (2025-03-01)

Prognostic value of Hematoxylin and eosin staining tumor-infiltrating lymphocytes (H&E-TILs) in patients with esophageal squamous cell carcinoma treated with chemoradiotherapy
Bằng: Jifang Zheng, et al.
Được phát hành: (2023-12-01)

The landscape of immune microenvironment in lung adenocarcinoma and squamous cell carcinoma based on PD‐L1 expression and tumor‐infiltrating lymphocytes
Bằng: Lu Chen, et al.
Được phát hành: (2019-12-01)

Commentary: Flow cytometry quantification of tumor-infiltrating lymphocytes to predict the survival of patients with diffuse large B-cell lymphoma
Bằng: Zhongling Sun, et al.
Được phát hành: (2024-04-01)

Prognostic Role of Tumor-Infiltrating Lymphocytes in Esophagus Cancer: a Meta-Analysis
Bằng: Xiao Zheng, et al.
Được phát hành: (2018-01-01)

Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango?
Bằng: Mohammad Hossein Kazemi, et al.
Được phát hành: (2022-10-01)

Clinical impact of heterogeneously distributed tumor-infiltrating lymphocytes on the prognosis of colorectal cancer
Bằng: Lu Liu, et al.
Được phát hành: (2024-01-01)

Excessive consumption of the sugar rich longan fruit promoted the development of nonalcoholic fatty liver disease via mediating gut dysbiosis
Bằng: Xu Wu, et al.
Được phát hành: (2023-03-01)

The association between CD3+ and CD8+tumor-infiltrating lymphocytes (TILs) and prognosis in patients with pancreatic adenocarcinoma
Bằng: Mahshid Panahi, et al.
Được phát hành: (2023-01-01)

Synthetic TILs: Engineered Tumor-Infiltrating Lymphocytes With Improved Therapeutic Potential
Bằng: Anaïs Jiménez-Reinoso, et al.
Được phát hành: (2021-02-01)

Glyoxalase 1 gene improves the antistress capacity and reduces the immune inflammatory response
Bằng: Fukuan Du, et al.
Được phát hành: (2019-12-01)

Decoding the epitranscriptome: a new frontier for cancer therapy and drug resistance
Bằng: Lu Tang, et al.
Được phát hành: (2024-10-01)

Gegen-Sangshen oral liquid and its active fractions mitigate alcoholic liver disease in mice through repairing intestinal epithelial injury and regulating gut microbiota
Bằng: Shulin Wei, et al.
Được phát hành: (2024-12-01)

Clinical significance of tumor-infiltrating lymphocytes investigated using routine H&E slides in small cell lung cancer
Bằng: Guangrun Zhou, et al.
Được phát hành: (2022-07-01)

Evaluation of tumor-infiltrating lymphocytes (TILs) in molecular subtypes of an Indian cohort of breast cancer patients
Bằng: Pooja M. Vaid, et al.
Được phát hành: (2022-11-01)

Transcriptomic characterization revealed that METTL7A inhibits melanoma progression via the p53 signaling pathway and immunomodulatory pathway
Bằng: Duoli Zhang, et al.
Được phát hành: (2023-08-01)

Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases
Bằng: Jiuping Zeng, et al.
Được phát hành: (2023-06-01)

Flow cytometry quantification of tumor-infiltrating lymphocytes to predict the survival of patients with diffuse large B-cell lymphoma
Bằng: Tiantian Yu, et al.
Được phát hành: (2024-01-01)