Immune response after rabies oral immunization in mice
The objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 10(7.5) DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral adminis...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Instituto de Tecnologia do Paraná (Tecpar)
2013-12-01
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| Series: | Brazilian Archives of Biology and Technology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006&lng=en&tlng=en |
| _version_ | 1818237030493061120 |
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| author | Camila Sloboda Pacheco da Silva Ernesto Renato Krüger Jorge Victor Bacila Agottani Rubens Chaguri de Oliveira Sandro Pereira Tânia Regina Penha Rüdiger Daniel Ollhoff |
| author_facet | Camila Sloboda Pacheco da Silva Ernesto Renato Krüger Jorge Victor Bacila Agottani Rubens Chaguri de Oliveira Sandro Pereira Tânia Regina Penha Rüdiger Daniel Ollhoff |
| author_sort | Camila Sloboda Pacheco da Silva |
| collection | DOAJ |
| description | The objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 10(7.5) DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral administration. Mice were vaccinated two times for seroconversion. Sera of the vaccinated mice showed a higher level of antibody production than the control group. These results could be used to direct the development of an anti-rabies oral vaccine. |
| first_indexed | 2024-12-12T12:19:17Z |
| format | Article |
| id | doaj.art-c8102f3980144bf7be11040c949c8583 |
| institution | Directory Open Access Journal |
| issn | 1678-4324 |
| language | English |
| last_indexed | 2024-12-12T12:19:17Z |
| publishDate | 2013-12-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-c8102f3980144bf7be11040c949c85832022-12-22T00:24:41ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1678-43242013-12-01566928931S1516-89132013000600006Immune response after rabies oral immunization in miceCamila Sloboda Pacheco da Silva0Ernesto Renato Krüger1Jorge Victor Bacila Agottani2Rubens Chaguri de Oliveira3Sandro Pereira4Tânia Regina Penha5Rüdiger Daniel Ollhoff6Pontifícia Universidade Católica do ParanáInstituto de Tecnologia do ParanáInstituto de Tecnologia do ParanáInstituto de Tecnologia do ParanáInstituto de Tecnologia do ParanáInstituto de Tecnologia do ParanáPontifícia Universidade Católica do ParanáThe objective of this study was to formulate an anti-rabies oral vaccine from the cell culture vaccine PV TECPAR to elicit the production of antibodies against the rabies in mice. A vaccine was developed using 10(7.5) DL50/0.03 ml viral antigens homogenised in lanovaseline to facilitate oral administration. Mice were vaccinated two times for seroconversion. Sera of the vaccinated mice showed a higher level of antibody production than the control group. These results could be used to direct the development of an anti-rabies oral vaccine.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006&lng=en&tlng=enRabiesOral vaccineMiceELISA |
| spellingShingle | Camila Sloboda Pacheco da Silva Ernesto Renato Krüger Jorge Victor Bacila Agottani Rubens Chaguri de Oliveira Sandro Pereira Tânia Regina Penha Rüdiger Daniel Ollhoff Immune response after rabies oral immunization in mice Brazilian Archives of Biology and Technology Rabies Oral vaccine Mice ELISA |
| title | Immune response after rabies oral immunization in mice |
| title_full | Immune response after rabies oral immunization in mice |
| title_fullStr | Immune response after rabies oral immunization in mice |
| title_full_unstemmed | Immune response after rabies oral immunization in mice |
| title_short | Immune response after rabies oral immunization in mice |
| title_sort | immune response after rabies oral immunization in mice |
| topic | Rabies Oral vaccine Mice ELISA |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132013000600006&lng=en&tlng=en |
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