Regulation of differentiation of annulus fibrosus-derived stem cells using heterogeneous electrospun fibrous scaffolds

Regulation of differentiation of annulus fibrosus-derived stem cells using heterogeneous electrospun fibrous scaffolds

Background: Tissue engineering of the annulus fibrosus (AF) shows promise as a treatment for patients with degenerative disc disease (DDD). However, it remains challenging due to the intrinsic heterogeneity of AF tissue. Fabrication of scaffolds recapitulating the specific cellular, componential, an...

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Bibliographic Details
Main Authors:	Pinghui Zhou, Genglei Chu, Zhangqin Yuan, Huan Wang, Weidong Zhang, Yingji Mao, Xuesong Zhu, Weiguo Chen, Huilin Yang, Bin Li
Format:	Article
Language:	English
Published:	Elsevier 2021-01-01
Series:	Journal of Orthopaedic Translation
Subjects:	Annulus fibrosus Annulus fibrosus-derived stem cells Cell differentiation Degenerative disc disease Fiber size
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X20300127

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