Syndecan-4 Mediates the Cellular Entry of Adeno-Associated Virus 9

Syndecan-4 Mediates the Cellular Entry of Adeno-Associated Virus 9

Due to their low pathogenicity, immunogenicity, and long-term gene expression, adeno-associated virus (AAV) vectors emerged as safe and efficient gene delivery tools, over-coming setbacks experienced with other viral gene delivery systems in early gene therapy trials. Among AAVs, AAV9 can translocat...

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Bibliographic Details
Main Authors: Anett Hudák, Matthew Roach, Dávid Pusztai, Aladár Pettkó-Szandtner, Annamária Letoha, László Szilák, Mimoun Azzouz, Tamás Letoha
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
AAV9
cellular entry
gene delivery
heparan sulfate proteoglycans
syndecans
Online Access:https://www.mdpi.com/1422-0067/24/4/3141

Internet

https://www.mdpi.com/1422-0067/24/4/3141

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