The prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhage
Abstract Background Comorbidities are common in aged intracerebral hemorrhage patients. The purpose of this study was to assess whether the Charlson Comorbidity Index (CCI) was associated with in-hospital death and short-term functional outcome in elderly patients (age ≥ 70) with intracerebral hemor...
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| Format: | Article |
| Language: | English |
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BMC
2022-11-01
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| Series: | BMC Neurology |
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| Online Access: | https://doi.org/10.1186/s12883-022-02980-z |
| _version_ | 1811207884854263808 |
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| author | Tianjie Zhang Ruiqi Chen Dingke Wen Xing Wang Lu Ma |
| author_facet | Tianjie Zhang Ruiqi Chen Dingke Wen Xing Wang Lu Ma |
| author_sort | Tianjie Zhang |
| collection | DOAJ |
| description | Abstract Background Comorbidities are common in aged intracerebral hemorrhage patients. The purpose of this study was to assess whether the Charlson Comorbidity Index (CCI) was associated with in-hospital death and short-term functional outcome in elderly patients (age ≥ 70) with intracerebral hemorrhage (ICH). Methods This was a retrospective cohort of aged ICH patients (≥70 years old) admitted within 24 hours of ICH onset. The CCI was derived using hospital discharge ICD-9 CM codes and patient history obtained from standardized case report forms. Multivariable logistic regression was used to determine the independent effect of the CCI score on clinical outcomes. Results In this cohort of 248 aged ICH patients, comorbid conditions were common, with CCI scores ranging from 2 to 12. Logistic regression showed that the CCI score was independently predictive of 1-month functional outcome (OR = 1.642, P < 0.001) and in-hospital death (OR = 1.480, P = 0.003). Neither ICH volume nor the presence of IVH was an independent predictive factor for 1-month functional outcome or in-hospital mortality (P < 0.05). Conclusion Comorbid medical conditions as assessed by the CCI independently influence short-term outcomes in aged ICH patients. The characteristics of the hematoma itself, such as ICH volume and the presence of IVH, seem to have a reduced effect on it. |
| first_indexed | 2024-04-12T04:12:29Z |
| format | Article |
| id | doaj.art-c820f9ddd0364b08be2f1d7c471e7783 |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-04-12T04:12:29Z |
| publishDate | 2022-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-c820f9ddd0364b08be2f1d7c471e77832022-12-22T03:48:29ZengBMCBMC Neurology1471-23772022-11-012211710.1186/s12883-022-02980-zThe prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhageTianjie Zhang0Ruiqi Chen1Dingke Wen2Xing Wang3Lu Ma4West China School of medicine, West China Hospital of Sichuan UniversityDepartment of Neurosurgery, West China Hospital of Sichuan UniversityDepartment of Neurosurgery, West China Hospital of Sichuan UniversityWest China School of medicine, West China Hospital of Sichuan UniversityDepartment of Neurosurgery, West China Hospital of Sichuan UniversityAbstract Background Comorbidities are common in aged intracerebral hemorrhage patients. The purpose of this study was to assess whether the Charlson Comorbidity Index (CCI) was associated with in-hospital death and short-term functional outcome in elderly patients (age ≥ 70) with intracerebral hemorrhage (ICH). Methods This was a retrospective cohort of aged ICH patients (≥70 years old) admitted within 24 hours of ICH onset. The CCI was derived using hospital discharge ICD-9 CM codes and patient history obtained from standardized case report forms. Multivariable logistic regression was used to determine the independent effect of the CCI score on clinical outcomes. Results In this cohort of 248 aged ICH patients, comorbid conditions were common, with CCI scores ranging from 2 to 12. Logistic regression showed that the CCI score was independently predictive of 1-month functional outcome (OR = 1.642, P < 0.001) and in-hospital death (OR = 1.480, P = 0.003). Neither ICH volume nor the presence of IVH was an independent predictive factor for 1-month functional outcome or in-hospital mortality (P < 0.05). Conclusion Comorbid medical conditions as assessed by the CCI independently influence short-term outcomes in aged ICH patients. The characteristics of the hematoma itself, such as ICH volume and the presence of IVH, seem to have a reduced effect on it.https://doi.org/10.1186/s12883-022-02980-zIntracerebral hemorrhageCharlson comorbidity indexOld patientsStroke outcomeComorbidity |
| spellingShingle | Tianjie Zhang Ruiqi Chen Dingke Wen Xing Wang Lu Ma The prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhage BMC Neurology Intracerebral hemorrhage Charlson comorbidity index Old patients Stroke outcome Comorbidity |
| title | The prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhage |
| title_full | The prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhage |
| title_fullStr | The prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhage |
| title_full_unstemmed | The prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhage |
| title_short | The prognostic value of the Charlson comorbidity index in aged patients with intracerebral hemorrhage |
| title_sort | prognostic value of the charlson comorbidity index in aged patients with intracerebral hemorrhage |
| topic | Intracerebral hemorrhage Charlson comorbidity index Old patients Stroke outcome Comorbidity |
| url | https://doi.org/10.1186/s12883-022-02980-z |
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