Secondary intracranial hypertension in aplastic anemia: A case report and review of current concepts

Intracranial hypertension (IH) when detected mandates prompt and appropriate therapy to avoid permanent visual impairment. We report a 7-year-old boy who presented to the emergency services with purpuric rashes and bruises. Peripheral blood smear and bone marrow aspiration confirmed the diagnosis of...

Full description

Bibliographic Details
Main Authors: Adil Al-Musalami, Alaa Elmanzalawy, Yasser Wali, Anuradha Ganesh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Oman Journal of Ophthalmology
Subjects:
Online Access:http://www.ojoonline.org/article.asp?issn=0974-620X;year=2021;volume=14;issue=3;spage=190;epage=195;aulast=Al-Musalami
Description
Summary:Intracranial hypertension (IH) when detected mandates prompt and appropriate therapy to avoid permanent visual impairment. We report a 7-year-old boy who presented to the emergency services with purpuric rashes and bruises. Peripheral blood smear and bone marrow aspiration confirmed the diagnosis of aplastic anemia. During admission, the child developed headache, nausea, vomiting, and diplopia. Ophthalmic examination revealed intermittent esotropia and bilateral papilledema. The findings on neuroimaging and lumbar puncture led to the diagnosis of secondary IH (SIH). The intracranial pressure normalized on treatment with oral acetazolamide, oral furosemide, and intravenous dexamethasone.
ISSN:0974-620X