Diagnosis of pathogens causing bacterial meningitis using Nanopore sequencing in a resource-limited setting

Diagnosis of pathogens causing bacterial meningitis using Nanopore sequencing in a resource-limited setting

Abstract Aim The aim of the present study is to compare the performance of 16S rRNA Nanopore sequencing and conventional culture in detecting infectious pathogens in patients with suspected meningitis in a resource-limited setting without extensive bioinformatics expertise. Methods DNA was isolated...

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Bibliographic Details
Main Authors: Srinivas Reddy Pallerla, Do Van Dong, Le Thi Kieu Linh, Trinh Van Son, Dao Thanh Quyen, Phan Quoc Hoan, Ngo Tat Trung, Nguyen Trong The, Jule Rüter, Sébastien Boutin, Dennis Nurjadi, Bui Tien Sy, Peter G. Kremsner, Christian G. Meyer, Le Huu Song, Thirumalaisamy P. Velavan
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Nanopore
Bacterial meningitis
Vietnam
16S rRNA
Next-generation sequencing
Diagnosis and pathogen genome
Online Access:https://doi.org/10.1186/s12941-022-00530-6

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